机构：[1]Capital Med Univ, Anzhen Hosp, Dept Gen Practice, Beijing 100029, Peoples R China;临床科室全科医疗科首都医科大学附属安贞医院[2]China Acad Chinese Med Sci Beijing, Xiyuan Hosp, Dept Cardiol, Beijing 100091, Peoples R China;[3]Beijing Jiaotong Univ, Sch Comp & Informat Technol, Beijing 100044, Peoples R China;[4]China Acad Chinese Med Sci, Beijing 100700, Peoples R China
Objective. Initial optimized prescription of Chinese herb medicine for unstable angina (UA). Methods. Based on partially observable Markov decision process model (POMDP), we choose hospitalized patients of 3 syndrome elements, such as qi deficiency, blood stasis, and turbid phlegm for the data mining, analysis, and objective evaluation of the diagnosis and treatment of UA at a deep level in order to optimize the prescription of Chinese herb medicine for UA. Results. The recommended treatment options of UA for qi deficiency, blood stasis, and phlegm syndrome patients were as follows: Milkvetch Root + Tangshen + Indian Bread + Largehead Atractylodes Rhizome (ADR = 0.96630); Danshen Root + Chinese Angelica + Safflower + Red Peony Root + Szechwan Lovage Rhizome Orange Fruit (ADR = 0.76); Snakegourd Fruit + Longstamen Onion Bulb + Pinellia Tuber + Dried Tangerine peel + Largehead Atractylodes Rhizome + Platycodon Root (ADR = 0.658568). Conclusion. This study initially optimized prescriptions for UA based on POMDP, which can be used as a reference for further development of UA prescription in Chinese herb medicine.
基金：
Beijing Committee of Science and Technology [D08050703020801]; TCM Public Welfare Scientific Research Project, State Administration of TCM of People's Republic of China [201007001]; National Key Basic Research Prescription of China [2006CB504803]; Twelve Five-year Plan of China [2013BAI02B01, 2013BAI13B01]; Beijing Anzhen Hospital [2013Z05]
第一作者机构：[1]Capital Med Univ, Anzhen Hosp, Dept Gen Practice, Beijing 100029, Peoples R China;
通讯作者：
通讯机构：[2]China Acad Chinese Med Sci Beijing, Xiyuan Hosp, Dept Cardiol, Beijing 100091, Peoples R China;
推荐引用方式(GB/T 7714)：
Feng Yan,Qiu Yu,Zhou Xuezhong,et al.Optimizing Prescription of Chinese Herbal Medicine for Unstable Angina Based on Partially Observable Markov Decision Process[J].EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE.2013,2013:-.doi:10.1155/2013/532534.
APA：
Feng, Yan,Qiu, Yu,Zhou, Xuezhong,Wang, Yixin,Xu, Hao&Liu, Baoyan.(2013).Optimizing Prescription of Chinese Herbal Medicine for Unstable Angina Based on Partially Observable Markov Decision Process.EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2013,
MLA：
Feng, Yan,et al."Optimizing Prescription of Chinese Herbal Medicine for Unstable Angina Based on Partially Observable Markov Decision Process".EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE 2013.(2013):-
