To summarize the characteristics of neurological symptoms in patients with aortic dissection. The clinical data including symptoms, signs, and imaging of 865 consecutive patients with aortic dissection were analyzed retrospectively. Neurological symptoms occurred in 225 cases (26.0%) with aortic dissection. The most common symptom was dizziness (56 cases, 6.5%), followed by syncope (49, 5.7%), single lower limb sensory disturbances (47, 5.4%), single lower extremity weakness (27, 3.1%), coma (22, 2.5%), paraplegia (19, 2.2%), headache (13,1.5%) and hemiplegia (9,1.0%). The first manifestation of five cases was the neurological symptoms, including syncope (2), dizziness (1) and headache (2). Patients with type A aortic dissection were more vulnerable to the neurological symptoms than those with type B aortic dissection (34.6% vs 14.7%), and the symptoms with significantly higher occurrence were syncope, coma, hemiplegia, paraplegia and lower limb sensory disturbances. Neurological symptoms are common in patients with aortic dissection,especially in those with type A aortic dissection.