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Assessing the Global Burden of Ischemic Heart Disease Part 1: Methods for a Systematic Review of the Global Epidemiology of Ischemic Heart Disease in 1990 and 2010

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机构： [1]Columbia Univ, Med Ctr, Dept Med, Div Gen Med, New York, NY 10027 USA; [2]Coll New Jersey, Coll New Jersey Lib, Ewing, NJ 08628 USA; [3]Shahid Sadoughi Univ Med Sci, Yazd Cardiovasc Res Ctr, Yazd, Iran; [4]Univ Washington, Inst Health Metr & Evaluat, Seattle, WA 98195 USA; [5]Columbia Univ, Augustus C Long Hlth Sci Lib, New York, NY 10027 USA; [6]Univ Washington, Sch Publ Hlth, Seattle, WA 98195 USA; [7]New York City Dept Hlth & Mental Hyg, New York, NY 11101 USA; [8]Columbia Univ, Mailman Sch Publ Hlth, New York, NY 10027 USA; [9]Columbia Univ Coll Phys & Surg, New York, NY 10032 USA; [10]Univ Queensland, Sch Populat, Brisbane, Qld, Australia; [11]London Sch Hyg & Trop Med, London, England; [12]Brigham & Womens Hosp, Dept Med, Div Gen Med, Boston, MA 02115 USA; [13]Univ Washington, Dept Med, Div Cardiol, Seattle, WA 98195 USA; [14]Beijing Inst Heart Lung & Blood Vessel Dis, Dept Epidemiol, Beijing, Peoples R China; [15]Capital Univ Med Sci, Beijing, Peoples R China; [16]South African Med Res Council, Chron Dis Lifestyle Res Unit, Durban, South Africa; [17]Univ Buenos Aires, Inst Clin Effectiveness & Hlth Policy, Buenos Aires, DF, Argentina; [18]Natl Res Ctr Prevent Med, Moscow, Russia; [19]Publ Hlth Fdn India, Ctr Chron Dis Control, New Delhi, India; [20]Imperial Coll London, MRC HPA Ctr Environm & Hlth, Dept Epidemiol & Biostat, London, England; [21]Univ Cape Town, Dept Med, Cape Town, South Africa

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BACK GROUND Ischemic heart disease (IHD) is the leading cause of death worldwide. The GBD ( Global Burden of Disease, Injuries, and Risk Factors) study (GBD 2010 Study) conducted a systematic review of IHD epidemiology literature from 1980 to 2008 to inform estimates of the burden on IHD in 21 world regions in 1990 and 2010. METHODS The disease model of IHD for the GBD 2010 Study included IHD death and 3 sequelae: myocardial infarction, heart failure, and angina pectoris. Medline, EMBASE, and LILACS were searched for IHD epidemiology studies in GBD high-income and low-and middle-income regions published between 1980 and 2008 using a systematic protocol validated by regional IHD experts. Data from included studies were supplemented with unpublished data from selected high-quality surveillance and survey studies. The epidemiologic parameters of interest were incidence, prevalence, case fatality, and mortality. RESULTS Literature searches yielded 40,205 unique papers, of which 1,801 met initial screening criteria. Upon detailed review of full text papers, 137 published studies were included. Unpublished data were obtained from 24 additional studies. Data were sufficient for high-income regions, but missing or sparse in many low-and middle-income regions, particularly Sub-Saharan Africa. CONCLUSIONS systematic review for the GBD 2010 Study provided IHD epidemiology estimates for most world regions, but highlighted the lack of information about IHD in Sub-Saharan Africa and other low-income regions. More complete knowledge of the global burden of IHD will require improved IHD surveillance programs in all world regions.

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大类 | 3 区医学

小类 | 3 区心脏和心血管系统

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第一作者机构： [1]Columbia Univ, Med Ctr, Dept Med, Div Gen Med, New York, NY 10027 USA;

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通讯机构： [1]Columbia Univ, Med Ctr, Dept Med, Div Gen Med, New York, NY 10027 USA;

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