机构：[1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China神经科系统神经内科首都医科大学宣武医院
出处：
ISSN：
摘要：
To explore the early diagnosis of germinoma originating from the basal ganglia (BG) and thalamus during juveniles. Retrospective analysis was done with the clinical cases of germinomas in BG and thalamus from 2000 to 2009. The symptoms, signs, neuroimaging, cerebrospinal fluid (CSF) findings were analyzed and related literature were reviewed. Eight patents were collected. The main symptoms were hemiplegia, associated with aphasia and/or impaired cognition. Brain CT showed high density and calcification. Abnormal T1 and T2 signal were found in brain MRI frequently associated with ipsilateral hemisphere atrophy. MRS showed increased choline and decreased N-acetylaspartate level. Elevated CSF human chorionic gonadotrophin level were found in two of them. Germinoma in BG and thalamus predominates in a boy. The neuroimaging features are very informative for early diagnosis.
语种：
外文
第一作者：
第一作者机构：[1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China
推荐引用方式(GB/T 7714)：
Wang X.L,Li C.J.The early diagnosis of juvenile germinoma originating from the basal ganglia and thalamus.[J].Zhonghua nei ke za zhi [Chinese journal of internal medicine].2011,50(4):
APA：
Wang, X.L&Li, C.J.(2011).The early diagnosis of juvenile germinoma originating from the basal ganglia and thalamus..Zhonghua nei ke za zhi [Chinese journal of internal medicine],50,(4)
MLA：
Wang, X.L,et al."The early diagnosis of juvenile germinoma originating from the basal ganglia and thalamus.".Zhonghua nei ke za zhi [Chinese journal of internal medicine] 50..4(2011)
