Proteomics-based approach was applied to analyze and compare the difference of proteins among human nasal inverted papilloma (NIP), nasal polyposis and normal nasal mucosa, in order to screen different proteins as marker. The total proteins of NIP, nasal polyposis and normal nasal mucosa were separated by two-dimensional gel electrophoresis (2-DE). Protein image obtained by using the gel of Calibrated GS-800 Densitometer system, and determined different protein spots. Six differential proteins between NIP and nasal polyp tissue were identified, which were galectin-1, Manganese-superoxide dismutase, galectin-7, trichostatin A, prohibitin and transferring. All of them were increased in NIP. Six differential proteins were possibly involved in NIP, which provided a new way for discriminating NIP from nasal polyposis. The data would be good for the establishment of NIP protein 2-DE map.
语种：
外文
PubmedID：
第一作者：
第一作者机构：[1]100069北京，首都医科大学宣武医院耳鼻咽喉头颈外科
通讯作者：
通讯机构：[2]北京世纪坛医院临床检验中心
推荐引用方式(GB/T 7714)：
孟庆书,靳胜,张秋航,et al.[Differential proteins analysis among human nasal inverted papilloma and nasal polyposis and normal nasal mucosa].[J].Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery.2010,45(4):314-7.
APA：
孟庆书,靳胜,张秋航&张曼.(2010).[Differential proteins analysis among human nasal inverted papilloma and nasal polyposis and normal nasal mucosa]..Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery,45,(4)
MLA：
孟庆书,et al."[Differential proteins analysis among human nasal inverted papilloma and nasal polyposis and normal nasal mucosa].".Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 45..4(2010):314-7
