机构：[1]Department of Neurology, Xuanwu Hospitol, Capital University of Medical Sciences, Beijing, 100053, China神经科系统神经内科首都医科大学宣武医院
出处：
ISSN：
摘要：
OBJECTIVE: To study ICAM-1, IL-1alpha expression in capillaries and to explore whether capillaries play a role in the pathogenesis of polymyositis. METHODS: Ten cases of patients with polymyositis and 6 patients with other myopathies were collected. CD34, ICAM-1 and IL-1alpha were selected for a quantitative measurement using an image analysis system, and results were presented as the percent of positive staining in the tissue area. RESULTS: We found that the percent of capillaries in tissues from polymyositis was significantly less than that from controls (P = 0.009). ICAM-1 and IL-1alpha expression in endothelial cells of capillaries were stronger in polymyositis patients. CONCLUSION: Our findings indicated that changes of capillaries might participate in the pathogenesis of polymyositis.
语种：
外文
第一作者：
第一作者机构：[1]Department of Neurology, Xuanwu Hospitol, Capital University of Medical Sciences, Beijing, 100053, China
推荐引用方式(GB/T 7714)：
Wang M,Jia J.P,Da Y.W.A study of vascular factor in the pathogenesis of polymyositis.[J].2005,44(2):
APA：
Wang, M,Jia, J.P&Da, Y.W.(2005).A study of vascular factor in the pathogenesis of polymyositis..,44,(2)
MLA：
Wang, M,et al."A study of vascular factor in the pathogenesis of polymyositis.". 44..2(2005)
