Aim: To understand the mental healthy condition of young managers in companies in different region. Methods: The young managers without any disease, who were under 40 years old, were selected randomly from two large state-owned enterprises that had the same scale and had gone on sale overseas from Beijing and Shandong province between August and December 2004, in which 68 were from Beijing state-owned enterprise and 96 from Shandong state-owned enterprise. The symptom checklist (SCL) (totally 90 items, 9 primary symptom dimensions: somatization, obsessive-compulsive, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, paranoid ideation and sychoticism etc., according to 5 grade score: 1: no, 2: mild, 3: moderate, 4: severe, 5: obvious severe) was used to test the testees, and compared with norms. Results: 164 managers were all involv ed in the result analysis, without drop. The scores of interpersonal sensitivity, depression, anxiety, hostility and phobic anxiety etc. in young managers of Beijing enterprise were lower than those of the norms (1.35±0.37,1.65±0.51;1.39±0.34,1.50±0.59; 1.26±0.26,1.39±0.43;1.38±0.37,1.48±0.56; 1.31±0.39,1.43±0.57,P <0.05,P<0.01). The scores of obsessive-compulsive,interpersonal sensitivity and depression etc. in young managers of Shandong enterprise were lower than those of norms (1.43±0.57,1.62±0.58;1.41±0.59,1.65 ±0.51;1.3 ±0.53,1.50±0.59;P < 0.05,P < 0.01). There was insignificant difference between the young managers of the Beijing and Shandong (P > 0.05). Conclusion: The status of mental health is good in young managers of enterprises in Beijing and Shandong region. The status of interpersonal sensitivity, depression, anxiety, hostility and paranoid ideation in managers of Beijing enterprise and the status of obsessive-compulsive, interpersonal sensitivity and depression in managers of Shandong enterprise are better than those of norms, besides, there is insignificant difference of the mental health between the personnel of the two enterprises.