摘要:
Aim. To investigate the correlation among episode, blood pressure, configuration of left ventricle and endothelial function in the teenagers with essential hypertensive disease (EH), and analyze the effect of motor intervention. Methods. Thirty-two adolescent patients with mild or moderate EH, aged 14-25 years, and twenty sex, age and body mass index (BMI) matched normotensive controls underwent 8 week aerobic exercise intervention, inquired ill history, personal history and family history. Ambulatory blood pressure monitoring (ABPM) and pulsed Doppler ultrasonography were applied in the all subjects for 24 hours. The supine position blood pressure and standing position blood pressure were measured with an arm sphygmomanometer after the subjects had rested for at least 15 minutes. Results. Approximately 94% of adolescent patients of mental labor with EH have a positive family history of EH, with a significant matrix effect. The incidence of obesity was higher and BMI was lower in the EH group compared with the control group. Clinical blood pressure(CBP) was positively correlated with ABP. CR was positively correlated to the average systolic blood pressure (SBP), diurnal SBP, night SBP and changes of standing position and supine position BP in the EH patients (r=0.5, 0.5, 0.4). The clinical BP, 24 hour average SBP and diurnal SBP were significantly lower after motor intervention, compared with those before motor intervention. Conclusion. Highly variability of blood pressure, a family history of hypertension and obesity are the significant characteristics of adolescent patients with EH. The lower BMI, positive family history, obesity and irascible adolescent persons are the high-risk group of EH. BMI, SBP and sympathetic nerve activity may be one of the influence factors of left ventricle reconstitution. Aerobic exercise is an efficient intervention treatment for ZEH in adolescent.