Six patients diagnosed as Psoriasis with complication of chylothorax (3 of chylothorax, 3 of both chylothorax and chyloperitoneum, age from 21 to 50, male 4, female 2) were reported. All patients have a history of taking a chinese medicine named "complex Wulong powder" for treating psoriasis. All patients have not the history of trauma, operation, and the history of living in epidemic focus of filariasis. Their X-ray exam and CT exam of chest did not show lung lesion but pleural effusion. Chylothorax coexisting with psoriasis was not found in literature. This result suggests that using complex WuLong powder might be the cause of chylothorax. The mechanism was unknown.