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The research advances of correlation between statin use and spontaneous intracerebral hemorrhage

他汀药物应用与脑出血相关性的研究进展

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收录情况: ◇ 统计源期刊 ◇ 北大核心 ◇ CSCD-C ◇ 中华系列

作者:
机构: [1]Department of Neurology, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing, 100070, China
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关键词: Cerebral hemorrhage Prognosis Statin

摘要:
Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, are established first line treatments for hypercholesterolemia because of their proved efficacy. However, the results of several studies have raised concerns that statin use increases the risk of spontaneous intracerebral hemorrhage(ICH). At the same time, other researches make the adverse conclusion that statin use does not increase the risk of ICH, but improves clinical outcome and decreases the mortality after ICH. Additional randomized controlled trials are required to clarify the correlation between statin use and ICH, and whether to continue statin use after ICH. This paper reviews research advances of correlation between statin use and ICH. Copyright © 2019 by the Chinese Medical Association.

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第一作者:
第一作者机构: [1]Department of Neurology, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing, 100070, China
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