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The characterisation of subjective cognitive decline.

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机构: [1]Department of Psychiatry, Medical Facultyand Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD),University of Cologne, Cologne,Germany [2]German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany [3]Center for Alzheimer Research and Treatment, [4]Department of Neurology , Brigham and Women’s Hospital and Department of Neurology Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA [5]Florey Institute University of Melbourne,Parkville, VIC, Australia [6]Melbourne School of Psychological Sciences,University of Melbourne,Parkville, VIC, Australia [7]Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience ,Amsterdam, Netherlands [8]Department of Epidemiology and Biostatistics, Vrije Universiteit Amsterdam, Amsterdam UMC,Amsterdam, Netherlands [9]Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China [10]Center of Alzheimer’s Disease, Beijing Institute for Brain Disorders, Beijing, China [11]Beijing Institute of Geriatrics, Beijing, China [12]National Clinical Research Center for Geriatric Disorders, Beijing, China [13]Alzheimer’s Disease and Other Cognitive Disorders Unit, Hospital Clínic, Barcelona, Spain [14]Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain [15]Department of Psychology, Brooklyn College and The Graduate Center of CUNY, Brooklyn, NY, USA [16]Department of Neurology, Albert Einstein College of Medicine, New York, NY, USA [17]Alzheimer Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, Spain [18]Department of Radiology and Imaging Sciences, [19]Indiana Alzheimer Disease Center, Indiana University School of Medicine,Indianapolis, IN, USA [20]Department of Medical and Molecular Genetics, Indiana University School of Medicine,Indianapolis, IN, USA [21]Department of Psychology,University of Victoria,Victoria, BC, Canada [22]Institute on Aging & Lifelong Health,University of Victoria,Victoria, BC, Canada [23]Department of Neurodegeneration and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany
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A growing awareness about brain health and Alzheimer's disease in the general population is leading to an increasing number of cognitively unimpaired individuals, who are concerned that they have reduced cognitive function, to approach the medical system for help. The term subjective cognitive decline (SCD) was conceived in 2014 to describe this condition. Epidemiological data provide evidence that the risk for mild cognitive impairment and dementia is increased in individuals with SCD. However, the majority of individuals with SCD will not show progressive cognitive decline. An individually tailored diagnostic process might be reasonable to identify or exclude underlying medical conditions in an individual with SCD who actively seeks medical help. An increasing number of studies are investigating the link between SCD and the very early stages of Alzheimer's disease and other neurodegenerative diseases. Copyright © 2020 Elsevier Ltd. All rights reserved.

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出版当年[2019]版:
大类 | 1 区 医学
小类 | 1 区 临床神经病学
最新[2023]版:
大类 | 1 区 医学
小类 | 1 区 临床神经病学
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出版当年[2018]版:
Q1 CLINICAL NEUROLOGY
最新[2023]版:
Q1 CLINICAL NEUROLOGY

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第一作者机构: [1]Department of Psychiatry, Medical Facultyand Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD),University of Cologne, Cologne,Germany [2]German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany [*1]Department of Psychiatry, University of Cologne, Cologne, 50924, Germany
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通讯机构: [1]Department of Psychiatry, Medical Facultyand Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD),University of Cologne, Cologne,Germany [2]German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany [*1]Department of Psychiatry, University of Cologne, Cologne, 50924, Germany
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