Background: Abundant evidence has proven the effectiveness of following an asthma action plan for children. China released its first children's asthma action plan in 2017 to improve asthma control. Objective: To assess the effectiveness of the Chinese Children's Asthma Action Plan (CCAAP) in the management of children with asthma. Methods: Children with persistent asthma (6-14 years old) at 10 tertiary hospitals were randomized to receive either CCAAP instructions (intervention group, n = 87) or no plan (control group, n = 86) in addition to the usual asthma care, including education, stepwise asthma therapy, and regular outpatient follow-up. Children were followed up by using a serial measurement of outcomes over the course of 3 months. Results: CCAAP instructions did not have a significant effect on any of outcomes compared with the intervention group: (1) variables related to asthma exacerbation, including the number of patients (p = 0.09), symptomatic days (p = 0.658), severity, medication (courses of reliever, p = 0.696; combined rhinitis medication, p = 0.081; combined oral antibiotics, p = 0.852), missed work days (p = 0.538) or school days (p = 0.441), and economic costs (p = 0.898); (2) asthma control (p = 0.180); or (3) pulmonary function parameters during the follow-up period. Both groups showed significant improvement in asthma control (both p < 0.001) and pulmonary function (p < 0.017) from baseline to the 3-month follow-up. Conclusion: The results of this study indicated that provision of CCAAP may play a useful role in the management of children with asthma, but there were no greater benefits than usual asthma care. We need to plan a larger appropriately powered study.