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Clinical and transmission dynamics characteristics of 406 children with coronavirus disease 2019 in China: A review

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机构: [a]Department of Respiratory Allergy, Beijing Children's Hospital of Beijing, Beijing, 102208, China [b]Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China [c]Children's Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430016, China [d]Department of Pediatrics, Gezhouba Central Hospital, Third Clinical Medical College of Three Gorges University, Yichang, Hubei [e]Department of Emergency, Children's Hospital, Capital Institute of Pediatrics, Beijing, 100020, China
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关键词: Children China Clinical Characteristics Coronavirus disease 2019 Transmission Ddynamics

摘要:
Objective: Chinese pediatricians are working on the front line to fight COVID-19. They have published a great amount of first-hand clinical data. Collecting their data and forming a large sample for analysis is more conducive to the recognition, prevention and treatment of coronavirus disease 2019 in children. The epidemic prevention and control experience of Chinese pediatricians should be shared with the world. Methods: By searching Chinese and English literature, the data of 406 children with COVID-19 in China were analyzed. Results: It was found that the clustered incidence of children's families is a dynamic transmission feature; the incidence is low; asymptomatic infections and mild cases account for 44.8%, with only 7 cases of critical illness; laboratory examination of lymphocyte counts is not reduced, as it is for adults; chest CT findings are less severe than those for adults. These presentations are the clinical features of COVID-19 in children. Only 55 of the 406 cases were tested by anal swab for virus nucleic acid, 45 of which were positive, accounting for 81.8% of stool samples. Conclusion: There are more children than adults with asymptomatic infections, milder conditions, faster recovery, and a better prognosis. Some concealed morbidity characteristics also bring difficulties to the early identification, prevention and control of COVID-19. COVID-19 screening is needed in the pediatric fever clinic, and respiratory and digestive tract nucleic acid tests should be performed. Efforts should be made to prevent children from becoming a hidden source of transmission in kindergartens, schools or families. Furthermore, China's experience in treating COVID-19 in children has led to faster recovery of sick children. © 2020 The British Infection Association

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出版当年[2019]版:
大类 | 2 区 医学
小类 | 2 区 传染病学
最新[2023]版:
大类 | 1 区 医学
小类 | 1 区 传染病学
第一作者:
第一作者机构: [a]Department of Respiratory Allergy, Beijing Children's Hospital of Beijing, Beijing, 102208, China [*1]Beijing Jindu Children’s Hospital, 308 huilongguan east street, changping district, Beijing 102208, China.
通讯作者:
通讯机构: [*1]Beijing Jindu Children’s Hospital, 308 huilongguan east street, changping district, Beijing 102208, China.
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