机构：[1]Department of Emergency Medicine, Beijing Chao-Yang Hospital, Capital Medical University, & Beijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation, Beijing 100020, China[2]Department of Emergency Medicine, Capital Medical University School of Rehabilitation Medicine, Beijing Bo’Ai Hospital, China Rehabilitation Research Center, Beijing 100068, China[3]Department of Geriatrics, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing 100053, China.内科系统老年医学科首都医科大学宣武医院
Background Frailty, at the core of geriatric medicine, is an important concept underpinning health problems but the rapid and valid measurement of frailty for older adults in the Emergency Department (ED) is lacking in China. The Frailty Screening Questionnaire (FSQ), has been shown to be a simple, rapid and practical tool to identify frailty in both community and inpatients settings, yet its utility in acute care settings is not well understood. Objective To determine whether FSQ is useful to identify frailty and predict adverse outcomes in an emergency care setting. Design and Participants This prospective study included 350 adults aged 60 and over and admitted to the ED. Measurements The FSQ questionnaire which assessed self-reported slowness, weakness, inactivity, exhaustion, and weight loss was used to rapidly recognize frailty. FRAIL, Clinical frailty score (CFS), activities of daily living (ADL) and nutrition risk screening 2002 were also assessed. Outcome measures included all-cause 28-day mortality, ADL dependency, mechanical ventilation, length of hospital stay, and ICU readmissions 30 and 90 days after discharge. Cox proportional hazard model was used for survival comparison. Results The prevalence of FSQ frailty and prefrailty in older adults were 44.6% and 30.9% respectively in the emergency setting. FSQ frailty was associated with increasing age, chronic diseases, malnutrition risk, poor physical function and worse outcomes indicated by higher 28-d mortality, ADL dependency, mechanical ventilation, length of hospital stay, and ICU readmissions after discharge. The Kappa coefficient between the FSQ and FRAIL was 0.552. FSQ score was negatively correlated with grip strength and positively correlated with Barthel index, length of hospital stay and CFS score. Cox regression adjusted by epidemiological variables and chronic diseases showed FSQ and all components predicted mortality except weight loss. Conclusion The FSQ is a rapid and useful tool to screen frailty and an effective tool to predict mortality in busy emergency settings.
基金：
This work was supported by Beijing Natural Science Foundation (7202059), Beijing Municipal Administration of Hospitals Incubating Program (PX2020036) and Milstein Medical Asian American Partnership Foundation Project Award in Geriatrics (2018).
第一作者机构：[1]Department of Emergency Medicine, Beijing Chao-Yang Hospital, Capital Medical University, & Beijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation, Beijing 100020, China[2]Department of Emergency Medicine, Capital Medical University School of Rehabilitation Medicine, Beijing Bo’Ai Hospital, China Rehabilitation Research Center, Beijing 100068, China
通讯作者：
通讯机构：[*1]Department of Geriatrics, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing 100053, China[*2]Department of Emergency Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation, Beijing 100020, China,
推荐引用方式(GB/T 7714)：
H. LIU,N. SHANG,J.K. CHHETRI,et al.A Frailty Screening Questionnaire (FSQ) to Rapidly Predict Negative Health Outcomes of Older Adults in Emergency Care Settings[J].JOURNAL OF NUTRITION HEALTH & AGING.2020,24(6):627-633.doi:10.1007/s12603-020-1374-8.
APA：
H. LIU,N. SHANG,J.K. CHHETRI,L. LIU,W. GUO...&L. MA.(2020).A Frailty Screening Questionnaire (FSQ) to Rapidly Predict Negative Health Outcomes of Older Adults in Emergency Care Settings.JOURNAL OF NUTRITION HEALTH & AGING,24,(6)
MLA：
H. LIU,et al."A Frailty Screening Questionnaire (FSQ) to Rapidly Predict Negative Health Outcomes of Older Adults in Emergency Care Settings".JOURNAL OF NUTRITION HEALTH & AGING 24..6(2020):627-633
