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Demographic characteristics and neuropsychological assessments of subjective cognitive decline (SCD) (plus)

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机构: [1]Department of General Practice, XuanWu Hospital of Capital Medical University, Beijing, China [2]Department of Geriatrics, XuanWu Hospital of Capital Medical University, Beijing, China [3]Department of Neurology, XuanWu Hospital of Capital Medical University, Beijing, China [4]Department of General Surgery, XuanWu Hospital of Capital Medical University, Beijing, China [5]Radiological Sciences, Division of Clinical Neuroscience, Queen’s Medical Centre, University of Nottingham, Nottingham, United Kingdom [6]National Clinical Research Center for Geriatric Disorders, Beijing, China [7]Center of Alzheimer’s Disease, Beijing Institute for Brain Disorders, Beijing, China
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Background Since SCD (plus) was standardized, little is known about its demographic characteristics and its outcomes of neuropsychological assessments, including the SCD questionnaire 9 (SCD-Q9). Objective To characterize SCD (plus) by comparing the neuropsychological features among its subgroups and with normal controls (NC). Also, to explore its demographics and to understand the relation of the chief complaints and the scores of SCD-Q9. Methods Multistage stratified cluster random sampling was conducted to select participants. As a result, 84 NC and 517 SCD (plus) were included. SCD (plus) was further classified into several subgroups (SCD-C: concerned cognitive decline; SCD-F: complaints about SCD within the past five years; SCD-P: feeling performance being not as good as their peers; SCD+: presented> 3 of SCD (plus) features; SCD-: presented <= 3 of SCD (plus) features (see the diagnostic criteria for the details)) and between-group comparisons of neuropsychological scores were conducted. Point-biserial correlation and binary logistic regression analyses were performed to investigate the demographic characteristics of its subgroups. Finally, Spearman correlation was used to better understand the relation of SCD (plus) to SCD-Q9. Results (1) Scores of AVLT-LR (AVLT-LR: Auditory Verbal Learning Test-Long Delayed Recall) and MoCA-B (MoCA: Montreal Cognitive Assessment-Basic) were lower in the SCD-P group than those in the NC group, and the SCD+ group scored lower in the MoCA-B and CDT(CDT: Clock Drawing Test) than the SCD- group. (2) Females were more concerned than male participants. Individuals with lower education level felt that their cognitive performance were worse than their peers. Also, younger people might express concerns more than the more elderly. People who had complaints of SCD-P might be more likely to report SCD-C, but less likely to report SCD-F. (3) Positive correlations were found between the chief complaints of SCD (plus) and some items of SCD-Q9. Conclusions SCD (plus) may be related to demographic factors. Individuals with SCD (plus) already exhibited cognitive impairment, which can be detected by SCD-Q9.

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出版当年[2019]版:
大类 | 2 区 医学
小类 | 2 区 临床神经病学 2 区 神经科学
最新[2023]版:
大类 | 2 区 医学
小类 | 2 区 临床神经病学 2 区 神经科学
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出版当年[2018]版:
Q1 CLINICAL NEUROLOGY Q1 NEUROSCIENCES
最新[2023]版:
Q1 CLINICAL NEUROLOGY Q1 NEUROSCIENCES

影响因子: 最新[2023版] 最新五年平均 出版当年[2018版] 出版当年五年平均 出版前一年[2017版] 出版后一年[2019版]

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第一作者机构: [1]Department of General Practice, XuanWu Hospital of Capital Medical University, Beijing, China [2]Department of Geriatrics, XuanWu Hospital of Capital Medical University, Beijing, China
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通讯机构: [*1]XuanWu Hospital of Capital Medical University, Beijing, China. [*2]Division of Clinical Neuroscience, Queen’s Medical Centre, University of Nottingham.
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