机构:[1]School of Public Health, Capital Medical University, 10 Xitoutiao, Youanmenwai, Fengtai, Beijing 100069, China[2]Beijing Municipal Key Laboratory of Clinical Epidemiology, 10 Xitoutiao, Youanmenwai, Fengtai, Beijing 100069, China[3]Department of Integrated Early Childhood Development, Capital Institute of Pediatrics, Beijing 100020, China首都儿科研究所[4]Institute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control, Beijing 100013, China[5]Department of Epidemiology & Public Health, University College Cork, Cork 78746, Ireland[6]Beijing Geriatric Clinical and Research Center, Xuanwu Hospital, Capital Medical University, Beijing 100053, China首都医科大学宣武医院
There have been few reports on the development of metabolic disorders, especially when they are considered as a cluster. The purpose of this study was to describe risk profiles for metabolic syndrome (MetS) in elderly dwellers in Beijing, and to find their transition patterns over time. Data were derived from Beijing longitudinal study of aging, a community-based cohort study hosted by Xuanwu hospital. There were 3,257 elderly people aged 55 years or over recruited in 1992. MetS was assessed for the years 1992, 2000, and 2009. Finally, 363 subjects with complete information for components of MetS in the three years were included in the study. The criteria of MetS recommended by the joint interim statement criteria were adopted. Latent transition analysis was used to calculate the transition probabilities between adjacent visits. A risk typology consisting of four time-invariant groups was detected based on the components of MetS for all subjects. Low MetS risk group, BP risk group, BP-HDL risk group, and BP-FPG-TG risk group were found. The probability of staying at the same status was higher at the two intervals across 18 years. Four latent groups were extracted based on three assessments for the components of MetS, together with their transition patterns. Findings suggested various trajectories for MetS components. Different combinations of intervention strategy might be needed for MetS risk groups.
基金:
The study has been funded by the Major Project
of Natural Science Fund of Beijing (Serial Number: 7131002); Key
Projects in the National Science & Technology Pillar Program in the
Twelfth Five-year Plan Period of China (2011BAI08B01); the Program
of Natural Science Fund of China (Serial Number: 81172772);
and the Program of Natural Science Fund of Beijing (Serial Number:
4112015).
第一作者机构:[1]School of Public Health, Capital Medical University, 10 Xitoutiao, Youanmenwai, Fengtai, Beijing 100069, China[2]Beijing Municipal Key Laboratory of Clinical Epidemiology, 10 Xitoutiao, Youanmenwai, Fengtai, Beijing 100069, China
共同第一作者:
通讯作者:
通讯机构:[1]School of Public Health, Capital Medical University, 10 Xitoutiao, Youanmenwai, Fengtai, Beijing 100069, China[2]Beijing Municipal Key Laboratory of Clinical Epidemiology, 10 Xitoutiao, Youanmenwai, Fengtai, Beijing 100069, China[5]Department of Epidemiology & Public Health, University College Cork, Cork 78746, Ireland
推荐引用方式(GB/T 7714):
Li-Xin Tao,Wei Wang,Hui-Ping Zhu,et al.Risk profiles for metabolic syndrome and its transition patterns for the elderly in Beijing, 1992-2009[J].ENDOCRINE.2014,47(1):161-168.doi:10.1007/s12020-013-0143-4.
APA:
Li-Xin Tao,Wei Wang,Hui-Ping Zhu,Da Huo,Tao Zhou...&Xiu-Hua Guo.(2014).Risk profiles for metabolic syndrome and its transition patterns for the elderly in Beijing, 1992-2009.ENDOCRINE,47,(1)
MLA:
Li-Xin Tao,et al."Risk profiles for metabolic syndrome and its transition patterns for the elderly in Beijing, 1992-2009".ENDOCRINE 47..1(2014):161-168