机构：[1]Department of Geriatric Medicine, Beijing Luhe Hospital, Capital Medical University, Beijing, China, Faculty of Information Technology, University of Jyväskylä, Jyväskylä, Finland.[2]State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.[3]Faculty of Information Technology, University of Jyväskylä, Jyväskylä, Finland, School of Biomedical Engineering, Faculty of Electronic Information and Electrical Engineering, Dalian University of Technology, Dalian, China.[4]Department of Geriatric Medicine, Beijing Luhe Hospital, Capital Medical University, Beijing, China.[5]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China, Beijing Key Laboratory of Neuromodulation, Capital Medical University, Beijing, China, Center of Epilepsy, Beijing Institute for Brain Disorders, Beijing, China.神经科系统科技平台神经内科脑功能疾病调控治疗北京市重点实验室首都医科大学宣武医院[6]Faculty of Information Technology, University of Jyväskylä, Jyväskylä, Finland.
Temperature-related reflex epilepsy most often takes the form of hot water epilepsy, but very rarely, reflex epilepsy is related to cold temperature. We report a 70-year-old male who had seizures triggered by cold sensations in the body. Four antiepileptic drugs were taken during the drug treatment, and oxcarbazepine was the most effective at stopping the seizures. We implemented clinical seizure induction and obtained EEG data from an interictal period and two complete ictal periods. Source estimation was performed to identify and map the primary sources involved in the seizures on the cortical level. We found that β rhythm appeared on the prefrontal lobes during the whole ictal period. The low-frequency slow δ and θ rhythms, especially the δ rhythm, appeared in the occipital lobe in the early ictal stage and propagated to the right temporal lobe in the mid-late ictal stage. The prefrontal lobe and right temporal lobe were mainly involved in the generation and propagation of the epileptic activities. This study provides a valuable reference for clinical drug therapy and provides insights into the characteristics of the brain activities involved in cold-induced reflex epilepsy. [Published with video sequences].
第一作者机构：[1]Department of Geriatric Medicine, Beijing Luhe Hospital, Capital Medical University, Beijing, China, Faculty of Information Technology, University of Jyväskylä, Jyväskylä, Finland.
推荐引用方式(GB/T 7714)：
Ren Ye,Li Xiaoli,Cong Fengyu,et al.EEG source estimation in a rare patient with cold-induced reflex epilepsy.[J].EPILEPTIC DISORDERS.2020,22(4):489-493.doi:10.1684/epd.2020.1185.
APA：
Ren Ye,Li Xiaoli,Cong Fengyu,Xiao Shuying,Zhang Qin...&Zhang Ruihua.(2020).EEG source estimation in a rare patient with cold-induced reflex epilepsy..EPILEPTIC DISORDERS,22,(4)
MLA：
Ren Ye,et al."EEG source estimation in a rare patient with cold-induced reflex epilepsy.".EPILEPTIC DISORDERS 22..4(2020):489-493
