机构:[1]Department of Neurology and China-America Institute ofNeuroscience, Capital Medical University, Beijing, China[2]Department of Radiology, Beth Israel Deaconess Medical Center,Boston, MA, USA[3]Department of Neurosurgery, Capital Medical University, Beijing, China[4]Department of Emergency, Capital Medical University, Beijing, China
The long-term functional outcome of acute basilar artery occlusion (BAO) patients who received modern endovascular therapy (EVT) is unclear. We sought to assess the long-term functional outcome of BAO patients treated with EVT and determine the prognostic factors associated with favorable outcome. We enrolled consecutive BAO patients who received EVT between December 2012 and December 2018 in this observational study. Baseline characteristics and outcomes were presented. Multivariable logistic regression analysis was performed to identify the prognostic factors associated with long-term outcome. Among the 177 BAO patients included in this study, 80 patients (45.2%) obtained favorable outcome and 97 patients (54.8%) had unfavorable outcome at long-term follow-up with a median observation time of 12 months (interquartile range, 3-19). A total of 67 patients (37.9%) died. National Institutes of Health Stroke Scale (NIHSS), posterior circulation Alberta Stroke Program Early Computed Tomography Score (pc-ASPECTS), time from stroke onset to recanalization, and recanalization condition were identified as independent predictors for long-term outcome. Over 40% of BAO patients who were treated with modern EVT achieved favorable outcome at long-term follow-up. NIHSS, pc-ASPECTS, time from stroke onset to recanalization, and recanalization condition were identified as independent prognostic factors of long-term outcome.
基金:
National Key Research and Development Program of China [2016YFC1301502, 2017YFC1308401]; National Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81771260, 81601006, 81620108011]
第一作者机构:[1]Department of Neurology and China-America Institute ofNeuroscience, Capital Medical University, Beijing, China
通讯作者:
通讯机构:[*1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
推荐引用方式(GB/T 7714):
Longfei Wu,Da Zhang,Jian Chen,et al.Long-term outcome of endovascular therapy for acute basilar artery occlusion[J].JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM.2021,41(6):1210-1218.doi:10.1177/0271678X20958587.
APA:
Longfei Wu,Da Zhang,Jian Chen,Chenghe Sun,Kangxiang Ji...&Xunming Ji.(2021).Long-term outcome of endovascular therapy for acute basilar artery occlusion.JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM,41,(6)
MLA:
Longfei Wu,et al."Long-term outcome of endovascular therapy for acute basilar artery occlusion".JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 41..6(2021):1210-1218