机构:[1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China神经科系统神经外科[2]Department of Functional Neurosurgery, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China首都医科大学附属天坛医院功能神经外科[3]Department of Neurology, University of Florida College of Medicine, Gainesville, FL, USA
Introduction Surgical treatments are considered for essential tremor (ET) when patients do not respond to oral pharmacological therapies. These treatments mainly comprise radiofrequency (RF) thalamotomy, gamma knife radiosurgery (GKRS), deep brain stimulation (DBS), and focused ultrasound (FUS) procedures. Areas covered We reviewed the strengths and weaknesses of each procedure and clinical outcomes for 7 RF studies (n = 85), 11 GKRS (n = 477), 33 DBS (n = 1061), and 13 FUS studies (n = 368). A formal comparison was not possible given the heterogeneity in studies. Improvements were about 42%-90% RF, 10%-79% GKRS, 45%-83% DBS, 42%-83% FUS at short-term follow-up (<12 months) and were about 54%-82% RF, 11%-84% GKRS, 18%-92% DBS, and 42%-80% FUS at long-term follow-up (>12 months). Expert opinion We found DBS with inherent advantages of being an adjustable and reversible procedure as the most frequently employed surgical procedure for control of ET symptoms. FUS is a promising procedure but has limited applicability for unilateral control of symptoms. RF is invasive, and GKRS has unpredictable delayed effects. Each of these surgical modalities has advantages and limitations that need consideration when selecting a treatment for the ET patients.
第一作者机构:[1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China[2]Department of Functional Neurosurgery, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China
共同第一作者:
通讯作者:
通讯机构:[*1]Norman Fixel Institute for Neurological Diseases, Gainesville, FL 32608, USA[3]Department of Neurology, University of Florida College of Medicine, Gainesville, FL, USA
推荐引用方式(GB/T 7714):
Wang Kai-Liang,Ren Qianwei,Chiu Shannon,et al.Deep brain stimulation and other surgical modalities for the management of essential tremor[J].EXPERT REVIEW OF MEDICAL DEVICES.2020,17(8):817-833.doi:10.1080/17434440.2020.1806709.
APA:
Wang, Kai-Liang,Ren, Qianwei,Chiu, Shannon,Patel, Bhavana,Meng, Fan-Gang...&Shukla, Aparna Wagle.(2020).Deep brain stimulation and other surgical modalities for the management of essential tremor.EXPERT REVIEW OF MEDICAL DEVICES,17,(8)
MLA:
Wang, Kai-Liang,et al."Deep brain stimulation and other surgical modalities for the management of essential tremor".EXPERT REVIEW OF MEDICAL DEVICES 17..8(2020):817-833