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Pycnidiophorones A-D, four new cytochalasans from the wetland derived fungus Pycnidiophora dispersa

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收录情况： ◇ SCIE ◇ EI

作者：

机构： [a]Department of Pharmacy, Xuanwu Hospital of Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing Engineering Research Center for Nervous System Drugs, Beijing Institute for Brain Disorders, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing 100053, China. [b]State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, People's Republic of China.

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Pycnidiophorones A-D (1-4), four new cytochalasans with a rare 5/6/6/5/6 pentacyclic skeleton incorporating the unique 12-oxatricyclo[6.3.1.0(2,7)]dodecane core, and six known depsidones (5-10) were isolated from cultures of the wetland-soil-derived fungus Pycnidiophora dispersa. Their chemical structures were unambiguously determined using NMR spectroscopic data. The absolute configurations of 1 and 3 were assigned by electronic circular dichroism (ECD) calculations. Compounds 1-10 showed moderate cytotoxicity against a panel of five human tumor cell lines.

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出版当年[2019]版：

大类 | 3 区化学

小类 | 3 区化学综合

最新[2023]版：

大类 | 3 区化学

小类 | 3 区化学：综合

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出版当年[2018]版：

Q2 CHEMISTRY, MULTIDISCIPLINARY

最新[2023]版：

Q2 CHEMISTRY, MULTIDISCIPLINARY

影响因子： 3.9 最新[2023版] 3.9 最新五年平均 3.049 出版当年[2018版] 3.168 出版当年五年平均 2.936 出版前一年[2017版] 3.119 出版后一年[2019版]

第一作者：

第一作者机构： [a]Department of Pharmacy, Xuanwu Hospital of Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing Engineering Research Center for Nervous System Drugs, Beijing Institute for Brain Disorders, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing 100053, China.

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