机构：[1]Xuanwu Hospital, Capital Medical University, Beijing, China,首都医科大学宣武医院[2]Liangxiang Teaching Hospital, Capital Medical University, Beijing, China,[3]Department of Research Collaboration, R&D Center, Beijing Deepwise and League of PHD Technology Co., Ltd., Beijing, China,[4]Neusoft Institute of Intelligent Healthcare Technology, Beijing, China,[5]The Second Affiliated Hospital of Harbin Medical University, Harbin, China,[6]The Third Central Hospital of Tianjin, Tianjin, China,[7]Sixth People’s Hospital of Xinjiang Autonomous Region, Xinjiang, China,[8]Central Hospital Hongxinglong Administration Bureau Youyi County, Shuangyashan, China,[9]Central Hospital Affiliated to Xinxiang Medical University, Xinxiang, China,[10]Harbin Chest Hospital, Harbin, China,[11]Shanxi Provincial People’s Hospital, Taiyuan, China,[12]Sichuan Provincial People’s Hospital, Chengdu, China,四川省人民医院[13]Langfang People’s Hospital, Hebei, China,[14]Beijing Chaoyang Hospital, Capital Medical University, Beijing, China,北京朝阳医院[15]Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States
The clinical spectrum of COVID-19 pneumonia is varied. Thus, it is important to identify risk factors at an early stage for predicting deterioration that require transferring the patients to ICU. A retrospective multicenter study was conducted on COVID-19 patients admitted to designated hospitals in China from Jan 17, 2020, to Feb 17, 2020. Clinical presentation, laboratory data, and quantitative CT parameters were also collected. The result showed that increasing risks of ICU admission were associated with age > 60 years (odds ratio [OR], 12.72; 95% confidence interval [CI], 2.42-24.61; P = 0.032), coexisting conditions (OR, 5.55; 95% CI, 1.59-19.38; P = 0.007) and CT derived total opacity percentage (TOP) (OR, 8.0; 95% CI, 1.45-39.29; P = 0.016). In conclusion, older age, coexisting conditions, larger TOP at the time of hospital admission are associated with ICU admission in patients with COVID-19 pneumonia. Early monitoring the progression of the disease and implementing appropriate therapies are warranted.
基金：
National Natural Science
Foundation of China (grant number 62041601 and 81801313),
the Beijing Municipal Science and Technology Planning
Project (Grant No. Z211100003521009) and the Beijing
Municipal Administration of Hospitals’ Youth Program (No.
QML 20180801).
第一作者机构：[1]Xuanwu Hospital, Capital Medical University, Beijing, China,
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Yan Chengxi,Chang Ying,Yu Huan,et al.Clinical Factors and Quantitative CT Parameters Associated With ICU Admission in Patients of COVID-19 Pneumonia: A Multicenter Study[J].FRONTIERS IN PUBLIC HEALTH.2021,9:doi:10.3389/fpubh.2021.648360.
APA：
Yan, Chengxi,Chang, Ying,Yu, Huan,Xu, Jingxu,Huang, Chencui...&Yang, Qi.(2021).Clinical Factors and Quantitative CT Parameters Associated With ICU Admission in Patients of COVID-19 Pneumonia: A Multicenter Study.FRONTIERS IN PUBLIC HEALTH,9,
MLA：
Yan, Chengxi,et al."Clinical Factors and Quantitative CT Parameters Associated With ICU Admission in Patients of COVID-19 Pneumonia: A Multicenter Study".FRONTIERS IN PUBLIC HEALTH 9.(2021)
