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Prevalence and Risk Factors Comparison of Anterior and Posterior Intracranial Arterial Stenosis.

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机构: [1]Department of Geriatrics, Xuanwu Hospital of Capital Medical University, Xicheng District, Beijing 100053, China. [2]Department of Vascular Ultrasound, Xuanwu Hospital of Capital Medical University, Xicheng District 100053, Beijing, China. [3]Evidence Based Medicine Center, Xuanwu Hospital of Capital Medical University, 45 Changchun Street, Xicheng District, Beijing 100053, China. [4]Department of Neurology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Changping District, Beijing 102218, China. [5]Department of Geriatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China. [6]Department of Neurology, Xuanwu Hospital of Capital Medical University, 45 Changchun Street, Xicheng District, Beijing 100053, China. [7]School of Clinical Medicine, Tsinghua University, 30 Shuangqing Road, Haidian District, Beijing 100084, China.
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The prevalence and risk factors of intracranial atherosclerotic stenosis (ICAS) located in the anterior circulation (AC) and posterior circulation (PC) has been scarcely noted in the general population. We aimed to determine ICAS prevalence and risk factor profile of AC and PC in a representative population. Data were from the China Hypertension Survey of Beijing. In total, 4800 people aged 35 years or older were enrolled in this subsurvey for ICAS, and 3954 participants were eligible for analysis. ICAS was assessed by transcranial Doppler. The prevalence of ICAS in AC was much greater than that in PC (11.9% vs. 4.2%), and subjects with ICAS in PC were 3.9 years older than those with ICAS in AC. Multivariable logistics regression showed that the odds of hypertension and diabetes increased by 79% (OR: 1.79, 95% CI: 1.40-2.27) and 35% (OR: 1.35, 95% CI: 1.04-1.75) in those with AC vascular lesions and by 3.35 times (OR: 3.35, 95% CI: 2.49-4.50) and 71% (OR: 1.71, 95% CI: 1.19-2.46) in those with PC vascular lesions compared with those without vascular lesions. Most modifiable vascular risk factors for ICAS appeared to exert similar magnitudes of risk for PC to AC lesions.Copyright © 2022 Yan Zhao et al.

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大类 | 4 区 医学
小类 | 4 区 全科医学与补充医学
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Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE
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第一作者机构: [1]Department of Geriatrics, Xuanwu Hospital of Capital Medical University, Xicheng District, Beijing 100053, China.
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通讯机构: [4]Department of Neurology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Changping District, Beijing 102218, China. [7]School of Clinical Medicine, Tsinghua University, 30 Shuangqing Road, Haidian District, Beijing 100084, China.
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