This study aimed to investigate the outcome of using three-dimensional (3D)-printed prostheses to reconstruct a cervical lateral mass to maintain cervical stability.We retrospectively analyzed data of seven patients requiring cervical lateral mass reconstruction using a 3D-printed prosthesis, comprising axial and subaxial lateral mass reconstruction in two and five patients, respectively. Bilateral mass was reconstructed in one patient and unilateral mass in the remaining six patients.Using a 3D-printed lateral mass prosthesis, internal fixation was stable for all seven patients postoperatively. No implant-related complications such as prosthesis loosening, displacement, and compression were observed at the last follow-up.Reconstruction of the lateral mass structure is beneficial in restoring load transfer in the cervical spine under physiological conditions. A 3D-printed prosthesis can be considered a good option for reconstruction of the lateral mass as fusion was achieved, with no subsequent complications observed.