The frequency and severity of symptoms of major depression in Chinese patients with chronic, medically unexplained, painful physical symptoms who present to a general neurology clinic
机构:[1]Department of Neurology, Xuan Wu Hospital, Capital Medical University, Beijing, China神经科系统神经内科首都医科大学宣武医院[2]ClinicPsychological Center, First Affi liated Hospital of Third Military Medical University, Chongqing, China[3]The General Hospital of the People’s Liberation Army, Beijing, China[4]Department of Neurology,Huanhu Hospital, Tianjin Neurological Central Hospital, Tianjin, China[5]West China Hospital, SichuanUniversity, Chengdu, China四川大学华西医院[6]Huashan Hospital of Fudan University, Shanghai, China[7]Eli LillyResearch Laboratories, Eli Lilly Canada, Toronto, Canada[8]Asia-Pacifi c Medical Communications, EliLilly Australia Pty Ltd, Sydney, NSW, Australia[9]Asia-Pacifi c Statistical Sciences, Eli Lilly AustraliaPty Ltd, Sydney, NSW, Australia[10]Medical Department, Eli Lilly Asia Inc., Shanghai, China
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摘要:
This cross-sectional, non-interventional, observational study evaluated depression in patients in China who presented to a general neurologist with chronic, medically unexplained, painful physical symptoms. Of the 402 patients enrolled, 197 patients (49.0%) met the criteria for a current major depressive episode (MDE+ group), as assessed using module A of the Mini International Neuropsychiatric Interview, and 205 patients (51.0%) did not (MDE- group). The mean pain severity visual analogue scale (VAS) score was significantly higher in the MDE+ group than the MDE- group (65.3 vs 55.6 mm; p<0.001). The mean depression severity score, as assessed using the 9-item Patient Health Questionnaire (PHQ-9), was 8.4 units (95% CI: 7.3 to 9.5) higher in the MDE+ group than the MDE- group (mean PHQ-9 total score: 14.8 vs 6.4). Anxiety and perceived health state were significantly worse, on average, in the MDE+ group (mean Hospital Anxiety and Depression Scale anxiety subscale score 10.7 vs 5.9 units; mean EuroQoL-5 Dimensions VAS score 56.4 vs 67.7 mm; each p0.001). Only 14.2% of patients had received treatment for depression during the past 3 months. These results suggest depression was common and may have been under-treated in this group of Chinese patients with chronic, medically unexplained painful physical symptoms.
语种:
外文
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出版当年[2010]版:
无
最新[2025]版:
大类|4 区医学
小类|4 区临床神经病学
第一作者:
第一作者机构:[1]Department of Neurology, Xuan Wu Hospital, Capital Medical University, Beijing, China
通讯作者:
通讯机构:[10]Medical Department, Eli Lilly Asia Inc., Shanghai, China[*1]Medical Department, Eli Lilly Asia Inc., 21F, 1 Corporate Avenue, 222 Hu Bin Road, Shanghai 200021, China.
推荐引用方式(GB/T 7714):
Jianping Jia,Wei Qu,Weiping Wu,et al.The frequency and severity of symptoms of major depression in Chinese patients with chronic, medically unexplained, painful physical symptoms who present to a general neurology clinic[J].Neurology Asia.2011,(4):
APA:
Jianping Jia,Wei Qu,Weiping Wu,Liyong Wu,Lingqiu Meng...&Shenghu Wu.(2011).The frequency and severity of symptoms of major depression in Chinese patients with chronic, medically unexplained, painful physical symptoms who present to a general neurology clinic.Neurology Asia,,(4)
MLA:
Jianping Jia,et al."The frequency and severity of symptoms of major depression in Chinese patients with chronic, medically unexplained, painful physical symptoms who present to a general neurology clinic".Neurology Asia ..4(2011)