机构:[1]Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing,China医技科室放射科首都医科大学宣武医院[2]Department of oncology, Southwest Hospital, Third Military Medical University,Chongqing, China[3]The Department of Biostatistics, School of Public Health and Tropical Medicine,Southern Medical University, Guangzhou, China
The aim was to investigate the effects of echo time (TE) on diffusion quantification of brain white matter. Seven rhesus monkeys (all males; age, 4-6 years; weight, 5-7 kg) underwent diffusion tensor imaging (DTI) with a series of TEs in 1.5 T and 3.0 T MR scanners. The mean diffusivity (MD), fractional anisotropy (FA), primary (lambda(1)), and transverse eigenvalues (lambda(23)) were measured in a region of interest at the bilateral internal capsule. Pearson correlation showed that the FA and lambda(1) increased and lambda(23) decreased with TE both at 1.5 T and 3.0 T except for the MD. Repeated measurement analysis of variance (ANOVA) also showed significantly higher FA and lower MD and lambda(23) at 3.0 T than those at 1.5 T (P<0.01), but no statistical differences were found in lambda(1) between these two field strengths (P=0.709). These findings implied that TE and field strength might influence diffusion quantification in brain white matter.
基金:
Natural Science Foundation of China; Grant numbers:
30470519 and 30670601; Grant sponsor: Beijing Scientific and Technological
New Star Program; Grant number: 2005B21; Grant sponsor: Program for New
Century Excellent Talents in University; Grant number: NCET-07-0568; Grant
sponsor: National High Technology Research and Development Program of
China; Grant number: 2006AA02z391.
第一作者机构:[1]Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing,China
通讯作者:
通讯机构:[1]Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing,China[*1]No. 45, Chang-Chun St., Xuanwu District, Beijing, China
推荐引用方式(GB/T 7714):
Qin W,Yu CS,Zhang F,et al.Effects of echo time on diffusion quantification of brain white matter at 1.5 T and 3.0 T.[J].MAGNETIC RESONANCE IN MEDICINE.2009,61(4):755-760.doi:10.1002/mrm.21920.
APA:
Qin W,Yu CS,Zhang F,Du XY,Jiang H...&Li KC.(2009).Effects of echo time on diffusion quantification of brain white matter at 1.5 T and 3.0 T..MAGNETIC RESONANCE IN MEDICINE,61,(4)
MLA:
Qin W,et al."Effects of echo time on diffusion quantification of brain white matter at 1.5 T and 3.0 T.".MAGNETIC RESONANCE IN MEDICINE 61..4(2009):755-760