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Carotid revascularization improves cognitive function in patients with asymptomatic carotid artery stenosis.

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机构: [1]Department of Vascular Surgery, Xuanwu Hospital and Institute of Vascular Surgery, CapitalMedical University, Beijing, China [2]Division of Vascular Surgery and Endovascular Therapy, Yale School of Medicine, New Haven, CT, USA [3]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China
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To investigate cognitive changes after carotid revascularization in elderly patients with asymptomatic carotid artery stenosis. We also compared cognitive outcomes of carotid endarterectomy with stenting in asymptomatic patients.From April 2019 to December 2019, patients with ≥70% asymptomatic carotid stenosis who were treated with CEA or CAS were recruited for this study. The Montreal cognitive assessment (MoCA) instrument was used to evaluate cognitive function preoperatively and postoperatively at 3, 6, and 12 months. The incidence of ipsilateral ischemic cerebrovascular events and restenosis were analyzed within 12 months.In 50 patients treated with CEA or CAS, baseline cognitive function was not different between CEA and CAS groups (P > 0.05). There was no difference in the incidence of ipsilateral ischemic cerebrovascular events and restenosis within the first 12 months between the two groups. There was a significant improvement in the total MoCA score, scores of attention, and delayed recall at 3, 6 and 12 months after revascularization compared with scores at baseline (all p<0.001). At 12 months, scores of cube copying and clock drawing were significantly improved (P=0.014, P=0.020). The clock drawing score was improved at 12 months after CAS compared with CEA (P=0.040).Carotid revascularization has a beneficial effect on cognition in asymptomatic patients within 12 months of the procedure. Compared with CEA, CAS show improved test scores of executive functioning by 1 year.Copyright © 2022 Elsevier Inc. All rights reserved.

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出版当年[2021]版:
大类 | 4 区 医学
小类 | 4 区 外科 4 区 外周血管病
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 外周血管病 4 区 外科
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出版当年[2020]版:
Q4 SURGERY Q4 PERIPHERAL VASCULAR DISEASE
最新[2023]版:
Q3 PERIPHERAL VASCULAR DISEASE Q3 SURGERY

影响因子: 最新[2023版] 最新五年平均 出版当年[2020版] 出版当年五年平均 出版前一年[2019版] 出版后一年[2021版]

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第一作者机构: [1]Department of Vascular Surgery, Xuanwu Hospital and Institute of Vascular Surgery, CapitalMedical University, Beijing, China
通讯作者:
通讯机构: [1]Department of Vascular Surgery, Xuanwu Hospital and Institute of Vascular Surgery, CapitalMedical University, Beijing, China [*1]No.45 Changchun Street, Xicheng District, Beijing 100053, China
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