研究单位：[1]Beijing Tiantan Hospital,Ministry of Science and Technology of the People´s Republic of China[2]Xuanwu Hospital, Capital Medical University,Beijing, Beijing, China, 100053[3]General Hospital of Rocket Army,Beijing, Beijing, China, 100088[4]Qilu Hospital, Shandong University,Jinan, Shandong, China, 250012[5]Qingdao Municipal Hospital,Qingdao, Shandong, China, 266034[6]Huashan Hospital, Fudan University,Shanghai, Shanghai, China, 200040[7]The Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou, Zhejiang, China, 310009
Complex brain arteriovenous malformations (bAVMs) in ≥3 Spetzler-Martin grades have long been challenges among cerebrovascular diseases. None of the traditional methods, such as microsurgical operation, endovascular intervention, or stereotactic radiotherapy, can completely eliminate complex bAVMs without a risk of neural function deterioration. The multistaged hybrid operation solved part of the challenge but remained risky in the installment procedures and intervals. The one-staged hybrid operation was applied in the surgical treatment of cerebrovascular diseases and proved to be a potentially safe and effective method for curing complex bAVMs. However, lacking the support of high-level evidence, its advantages remain unclear. This study was proposed to validate the benefits and risks of one-staged hybrid operation in the treatment of complex bAVMs, as well as its indications, key technologies, and workflows.
