Phase 3, Double-blind, Randomized, Placebo-controlled Trial to Evaluate the Efficacy and Safety of AR1001 in Participants with Early Alzheimer's Disease (Polaris-AD)
研究单位：[1]Stanford University[2]AriBio Co., Ltd.[3]IMA Clinical Research Phoenix,Phoenix,Arizona,United States,85012[4]Perseverance Research Center, LLC,Scottsdale,Arizona,United States,85253[5]Clinical Endpoints - N. Scottsdale,Scottsdale,Arizona,United States,85258[6]Banner Sun Health Research Institute,Sun City,Arizona,United States,85351[7]Voyage Medical,Tempe,Arizona,United States,85282[8]Sutter Health's Palo Alto Medical Foundation,Burlingame,California,United States,94010[9]Neuro-Pain Medical Center,Fresno,California,United States,93710[10]Fullerton Neurology and Headache Center,Fullerton,California,United States,92835[11]Esperanza Clinical,Murrieta,California,United States,92562[12]Valley Clinical Trials, INC,Northridge,California,United States,91325[13]Havana Research Institute,Pasadena,California,United States,91105[14]Kaizen Brain Center,San Diego,California,United States,92037[15]Adaptive Research,San Jose,California,United States,95124[16]The Neuron Clinic,San Marcos,California,United States,92069[17]Stanford Neuroscience Health Center,Stanford,California,United States,94305[18]Denver Neurological Research,Denver,Colorado,United States,80210[19]Mile High Research Center,Denver,Colorado,United States,80218[20]CenExel Rocky Mountain Clinical Research,Englewood,Colorado,United States,80113[21]Topaz Clinical Research,Apopka,Florida,United States,32803[22]BayCare Health System, Inc,Clearwater,Florida,United States,33756[23]Vertex Research Group,Clermont,Florida,United States,34711[24]Arrow Clinical Trial,Daytona Beach,Florida,United States,32117[25]Brainstorm Research - Loxahatchee,Loxahatchee Groves,Florida,United States,33470[26]ClinCloud LLC,Maitland,Florida,United States,32751[27]Meridian International Research, Inc,Miami Gardens,Florida,United States,33014[28]Verus Clinical Research, Corp,Miami,Florida,United States,33135[29]Vitae Research Center, LLC,Miami,Florida,United States,33135[30]Caro Medcenter and Community Research,Miami,Florida,United States,33145[31]Allied Biomedical Research Institute, Inc,Miami,Florida,United States,33155[32]Future Life Clinical Trials,Miami,Florida,United States,33169[33]Brainstorm Research,Miami,Florida,United States,33176[34]Charter Research - Orlando,Orlando,Florida,United States,32803[35]K2 Medical Research,Orlando,Florida,United States,32806[36]JEM Research Institute,Palm Beach,Florida,United States,33462[37]Progressive Medical Research,Port Orange,Florida,United States,32127[38]Angels Clinical Research Institute, Inc. - Tampa,Tampa,Florida,United States,33614[39]Charter Research - The Villages,The Villages,Florida,United States,32162[40]ClinCloud, LLC Melbourn,Viera,Florida,United States,32940[41]Conquest Research,Winter Park,Florida,United States,32789[42]iResearch -Atlanta,Atlanta,Georgia,United States,30030[43]Atlanta Neuroscience Institute,Atlanta,Georgia,United States,30327[44]Accel Research Sites,Decatur,Georgia,United States,30030[45]iResearch,Savannah,Georgia,United States,31405[46]Re:Cognition Health - Chicago,Chicago,Illinois,United States,60611[47]Tandem Clinical Research,New Orleans,Louisiana,United States,70072[48]BTC of New Bedford,New Bedford,Massachusetts,United States,02740[49]Boston Center for Memory,Newton,Massachusetts,United States,02459[50]Headlands Research - Eastern MA,Plymouth,Massachusetts,United States,02360[51]Boston Paincare,Waltham,Massachusetts,United States,02451[52]Sharlin Health Neuroscience Research Center,Ozark,Missouri,United States,65721[53]Alivation,Lincoln,Nebraska,United States,68526[54]Wake Research- Clinical Research Center of Nevada, LLC,Las Vegas,Nevada,United States,89106[55]Advanced Memory Research Institute of New Jersey,Toms River,New Jersey,United States,08755[56]Dent Neuroscience Research Center,Amherst,New York,United States,14226[57]Mid-Hudson Medical Research, PLLC - New Windsor,New Windsor,New York,United States,12553[58]Triad Clinical Trials,Greensboro,North Carolina,United States,27410[59]AMC Research, LLC,Matthews,North Carolina,United States,28105[60]Accellacare of Winston-Salem, Triad Neurological Associates,Winston-Salem,North Carolina,United States,27103[61]NeuroScience Research Center, LLC,Canton,Ohio,United States,44718[62]American Clinical Research Institute, LLC,Dayton,Ohio,United States,45432[63]Rhode Island Mood and Memory Research,East Providence,Rhode Island,United States,02914[64]Health Concepts,Rapid City,South Dakota,United States,57702[65]Neurology Clinic, P.C.,Cordova,Tennessee,United States,38018[66]Center for Biomedical Research, LLC - Genesis Neuroscience Clinic,Knoxville,Tennessee,United States,37909[67]Gadolin Research LLC,Beaumont,Texas,United States,77702[68]Kerwin Medical Center,Dallas,Texas,United States,75231[69]Cognition Health Corporation- Texas,Houston,Texas,United States,77030[70]Clinical Trial Network - Houston,Houston,Texas,United States,77074[71]Bhupesh Dihenia, MD, PA,Lubbock,Texas,United States,79410[72]Wasatch Clinical Research, LLC,Salt Lake City,Utah,United States,84107[73]Cognition Health Corporation,Fairfax,Virginia,United States,22031[74]Integrated Neurology Services,Falls Church,Virginia,United States,22043[75]Kingfisher Cooperative,Spokane,Washington,United States,99201[76]Vaught Neurological Services, PLLC,Crab Orchard,West Virginia,United States,25827[77]Medical College of Wisconsin,Wauwatosa,Wisconsin,United States,53226[78]Xuanwu Hospital Capital Medical University,Beijing,China
This AR1001-ADP3-US01 protocol is a double-blind, randomized, placebo-controlled, multi- center, parallel-group comparison pivotal Phase 3 study to evaluate the efficacy and safety of AR1001 for the treatment of participants with early AD.
