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LTA-guided Antiplatelet Therapy in Interventional Treatment of Intracranial Aneurysms

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研究单位: [1]Department of Neurosurgery, Beijing Tiantan Hospital.,Beijing,Beijing,China,100070 [2]Xuanwu Hospital, Beijing [3]Chinese PLA General Hospital [4]Beijing Chao Yang Hospital [5]Peking University International Hospital [6]Peking University First Hospital [7]Hebei Medical University Third Hospital [8]Tianjin Medical University General Hospital [9]Beijing Tiantan hospital,Beijing,Beijing,China,100070

关键词: Intracranial Aneurysm Interventional Therapy Stent Platelet Ischemic Stroke

研究目的:
The use of intracranial stents broadens the indications for endovascular treatment of intracranial aneurysms and improves the cure rate, but it also increases the risk of postoperative ischemic complications in patients. The current standard dual antiplatelet regimen is considered to be an important method to reduce thrombotic events. However, some patients are resistant to antiplatelet drugs and have a high risk of thrombotic events. In actual clinical work, the standards for platelet function testing are not standardized, and the antiplatelet drug adjustment program also lacks norms and consensus. This study carried out a multi-center, prospective cluster randomized controlled study to explore whether the standardized antiplatelet adjustment program guided by LTA detection can reduce the incidence of ischemic events after stent implantation in patients with intracranial unruptured aneurysms. Further determine and correct the curative effect of the standardized use of antiplatelet drugs in the treatment of intracranial aneurysm stents, and finally formulate a set of standardized antiplatelet regimens.

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