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An Efficacy and Safety Study of Sodium Oligomannate (GV-971) for the Treatment of Alzheimer's Disease

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研究单位： [1]Green Valley (Shanghai) Pharmaceuticals Co., Ltd. [2]Beijing Anding Hospital, Capital Medical University,Beijing,Beijing,China [3]Beijing Hospital,Beijing,Beijing,China [4]Xuanwu Hospital, Capital Medical University,Beijing,Beijing,China [5]The First Affiliated Hopsital of Xiamen University,Xiamen,Fujian,China [6]The First Affiliated Hopsital of Guangzhou Medical University,Guangzhou,Guangdong,China [7]The Second Affiliated Hopsital of Guangzhou Medical University,Guangzhou,Guangdong,China [8]The First People's Hospital of Nanning,Nanning,Guangxi,China [9]Shijiazhuang People's Hospital,Shijiazhuang,Hebei,China [10]The First Hospital of Hebei Medical University,Shijiazhuang,Hebei,China [11]The Second Hopsital of Hebei Medical University,Shijiazhuang,Hebei,China [12]Tangshan Workers' Hospital,Tangshan,Hebei,China [13]The First Affiliated Hopsital of Nanyang Medical College,Nanyang,Henan,China [14]Henan Provincial People's Hospital,Zhengzhou,Henan,China [15]Chenzhou First People's Hospital,Chenzhou,Hunan,China [16]Yueyang Central Hospital,Yueyang,Hunan,China [17]Huai'an Second People's Hospital,Huai'an,Jiangsu,China [18]Nanjing Brain Hospital,Nanjing,Jiangsu,China [19]Affiliated Hospital of Nantong University,Nantong,Jiangsu,China [20]The Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu,China [21]Yangzhou First People's Hospital,Yangzhou,Jiangsu,China [22]Jiujiang University Affiliated Hospital,Jiujiang,Jiangxi,China [23]The Second Affiliated Hopsital of Nanchang University,Nanchang,Jiangxi,China [24]The First Bethune Hospital of Jilin University,Changchun,Jilin,China [25]Qilu Hospital of Shandong University,Jinan,Shandong,China [26]Shandong Provincial Hospital,Jinan,Shandong,China [27]Yantai Yuhuangding Hospital,Yantai,Shandong,China [28]Tianjin People's Hospital,Tianjin,Tianjin,China [29]The Second Hospital of Jiaxing,Jiaxing,Zhejiang,China

研究目的：

The primary purpose of this study is to confirm the clinical efficacy and mechanism of action of GV-971, and identify incidence of known adverse reactions in long-term use and observe new adverse reactions, providing more guidance for clinical use.