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A Phase III Study to Evaluate the Efficacy and Safety of AK111 in Subjects With Active Ankylosing Spondylitis

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研究单位: [1]Akeso [2]1006-The First Affiliated Hospital of Bengbu Medical University,Bengbu,Anhui,China [3]1038-Anhui Provincial Hospital,Hefei,Anhui,China [4]1001-Peking University Third Hospital,Beijing,Beijing,China [5]1002-Xuanwu Hospital Capital Medical University,Beijing,Beijing,China [6]1042-Peking University Shougang Hospital,Beijing,Beijing,China [7]1049-The First Affiliated Hospital of Xiamen University,Xiamen,Fujian,China [8]1027-Lanzhou University Second Hospital,Lanzhou,Gansu,China [9]1005-Nanfang Hospital,Guangzhou,Guangdong,China [10]1025-Guangzhou First People's Hospital,Guangzhou,Guangdong,China [11]1030-Jieyang People's Hospital,Jieyang,Guangdong,China [12]1008-The Seventh Affiliated Hospital, Sun Yat-sen University,Shenzhen,Guangdong,China [13]1026-Shenzhen People's Hospital,Shenzhen,Guangdong,China [14]1056-Zhongshan Traditional Chinese Medicine Hospital,Zhongshan,Guangdong,China [15]1024-Liuzhou People's Hospital,Liuzhou,Guangxi,China [16]1021-The People's Hospital of Guangxi Zhuang Autonomous Region,Nanning,Guangxi,China [17]1022-The First Affiliated Hospital of Hainan Medical University,Haikou,Hainan,China [18]1034-Affiliated Hospital of Hebei University,Baoding,Hebei,China [19]1012-Hebei Petro China Central Hospital,Langfang,Hebei,China [20]1029-Hebei General Hospital,Shijiazhuang,Hebei,China [21]1033-The First Hospital of Qiqihar,Qiqihar,Heilongjiang,China [22]1045-The First Affiliated Hospital of Henan University of Science and Technology,Luoyang,Henan,China [23]1053-Nanyang Central Hospital,Nanyang,Henan,China [24]1051-Shiyan People's Hospital,Shiyan,Hubei,China [25]1031-The First Affiliated Hospital of University of South China,Hengyang,Hunan,China [26]1032-Yueyang Central Hospital,Yueyang,Hunan,China [27]1011-Zhuzhou Central Hospital,Zhuzhou,Hunan,China [28]1017-Changzhou NO.2 People's Hospital,Changzhou,Jiangsu,China [29]1037-The Second People's Hospital of Lianyungang,Lianyungang,Jiangsu,China [30]1004-Zhongda Hospital Southeast University,Nanjing,Jiangsu,China [31]1007-Nanjing Drum Tower Hospital,Nanjing,Jiangsu,China [32]1036-Jiangsu Province Hospital,Nanjing,Jiangsu,China [33]1018-Affiliated Hospital of Nantong University,Nantong,Jiangsu,China [34]1035-Wuxi People's Hospital,Wuxi,Jiangsu,China [35]1013-Xuzhou Central Hospital,Xuzhou,Jiangsu,China [36]1014-Affiliated Hospital of Jiangsu University,Zhenjiang,Jiangsu,China [37]1047-The First Affiliated Hospital of Gannan Medical College,Ganzhou,Jiangxi,China [38]1020-The Second Affiliated Hospital of Nanchang University,Nanchang,Jiangxi,China [39]1039-The First Affiliated Hospital of Nanchang University,Nanchang,Jiangxi,China [40]1046-Pingxiang People's Hospital,Pingxiang,Jiangxi,China [41]1044-Jilin Provincial People's Hospital,Changchun,Jilin,China [42]1028- Jining First People's Hospital,Jining,Shandong,China [43]1019-Linyi City People Hospital,Linyi,Shandong,China [44]1055-Weifang People's Hospital,Weifang,Shandong,China [45]1016-Zaozhuang Municipal Hospital,Zaozhuang,Shandong,China [46]1054-Linfen Central Hospital,Linfen,Shanxi,China [47]1009-Second Hospital of Shanxi Medical University,Taiyuan,Shanxi,China [48]1043-Yuncheng Central Hospital,Yuncheng,Shanxi,China [49]1010-West China Hospital,Sichuan University,Chengdu,Sichuan,China [50]1048-Mianyang Central Hospital,Mianyang,Sichuan,China [51]1041-Affiliated Hospital of North Sichuan Medical College,Nanchong,Sichuan,China [52]1023-The People's Hospital of Xinjiang Uyghur Autonomous Region,Urumqi,Xinjiang,China [53]1040- Huzhou Third People's Hospital,Huzhou,Zhejiang,China [54]1015-Taizhou Hospital of Zhejiang Province,Taizhou,Zhejiang,China [55]1050-The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,Zhejiang,China

研究目的:
This is a randomized, double-blind, placebo-controlled, multi-center phase III clinical study to evaluate the efficacy and safety of AK111 in the treatment of subjects with active ankylosing spondylitis.

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