研究单位：[1]Peking Union Medical College Hospital,Beijing,Beijing,China,100730[2]Fu Xing Hospital, Capital Medical University[3]West China Hospital Affiliated with Sichuan University[4]First Hospital of China Medical University[5]Shanghai Zhongshan Hospital[6]The First Hospital of Jilin University[7]China-Japan Friendship Hospital[8]Beijing Friendship Hospital of Captial Medical University (Beijing)[9]Beijing Chao Yang Hospital[10]General Hospital of Ningxia Medical University[11]Xiangya Hospital of Central South University[12]Beijing Tongren Hospital[13]Peking University Third Hospital[14]Xuanwu Hospital, Beijing[15]Beijing Tiantan Hospital[16]Guangdong Provincial People’s Hospital
The goal of this observational study is to learn about the roles of critical closing pressure and tissue perfusion pressure in monitoring hemodynamic status, evaluating organ damage, and predicting mortality risk in patients with sepsis. The main question it aims to answer is: • Whether increases in critical closing pressure or tissue perfusion pressure are associated with a reduced risk of poor prognosis? Within the 24 hours following the diagnosis of sepsis, patients will be categorized into four groups based on their 24-hour mean critical closing pressure and tissue perfusion pressure. Outcomes will then be compared across these different groups. The study has been approved by the Medical Ethics Committee of Peking Union Medical College Hospital (K24C1937).
