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MEDI4736 用于非小细胞肺癌辅助治疗的研究

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研究单位: [1]广东省人民医院 [2]中山大学肿瘤防治中心 [3]复旦大学附属中山医院 [4]北京大学肿瘤医院 [5]北京大学人民医院 [6]福建省肿瘤医院 [7]河南省肿瘤医院 [8]山东省肿瘤医院 [9]云南省肿瘤医院 [10]浙江大学医学院附属邵逸夫医院 [11]中南大学湘雅二院 [12]华中科技大学同济医学院附属协和医院 [13]南京军区南京总医院 [14]苏北人民医院 [15]徐州医科大学附属医院 [16]广西壮族自治区人民医院 [17]青岛大学附属医院 [18]University of Florida - Gainesville [19]Beaver Medical Group,L.P. [20]USC Norris Comprehensive Cancer Center [21]Thomas Jefferson University [22]H. Lee Moffitt Cancer Center [23]Duke University [24]National Jewish Health [25]Reading Hospital McGlinn Cancer Institute [26]Hematology & Oncology Associates of NEPA [27]Ausl 6 Ospedale Civile Livorno - Istituto Toscano Tumori [28]Centro di Riferimento Oncologico Oncologia Medica A [29]A.S.L. 3 Genovese - Ospedale Villa Scassi [30]Azienda Ospedaliera “San Giuseppe Moscati [31]Azienda Ospedaliera San Camillo-Forlanini [32]Istituto per lo Studio e la Cura dei Tumori, [33]I.R.C.C.S. Istituto Oncologico Veneto [34]Azienda Ospedaliera G. Rummo [35]A.S.L. Brindisi Presidio Ospedaliero Senatore Antonio Perrino [36]Strutture Ospedaliere ULSS 13 - Mirano [37]Istituto Europeo di Oncologia [38]Presidio Ospedaliero di Saronno AO Di Busto Arsizio [39]Azienda Ospedaliera Universitaria Seconda Università degli Studi di Napoli [40]IRCCS Azienda Ospedaliera Universitaria San Martino [41]IRCCS - Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) [42]Az. USL di Piacenza Ospedale Guglielmo da Saliceto [43]Humanitas Cancer Center,Istituto Clinico Humanitas [44]Azienda Ospedaliera di Rilievo Nazionale A.O.R.N. “Antonio Cardarelli” U.O.S.C. Oncologia [45]Università di Napoli Federico II [46]Azienda Ospedaliera Universitaria Integrata Verona - Policlinico GB Rossi [47]Istituti Fisioterapici Ospitalieri - IFO - Istituto Regina Elena [48]Azienda Ospedaliera Universitaria Policlinico Vittorio Emanuele Presidio Ospedaliero Gaspare Rodolico [49]Azienda Ospedaliero-Universitaria Ospedali Riuniti Umberto I-Lancisi-Salesi [50]Azienda Ospedaliera di Perugia (S.M della Misericordia) [51]I.R.C.C.S Ospedale Oncologico Giovanni Paolo II Bari [52]Fondazione Salvatore Maugeri Clinica del Lavoro e della Riabilitazione I.R.C.C.S . [53]Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) S.r.l,IRCCS [54]Tri-Service General Hospital [55]Veterans General Hospital -Taipei [56]Chang-Gung Medical Foundation,Linkou [57]China Medical University Hospital [58]Chang Gung Memorial Hospital,Chia-Yi [59]Chang Gung Memorial Hospital,Kaohsiung [60]Kaohsiung Medical University Chung-Ho Memorial Hospital [61]Taipei Medical University - Shuang Ho Hospital,MOHW [62]Mackay Memorial Hospital [63]Hualien Tzu Chi Hospital [64]Far Eastern Memorial Hospital [65]The Catholic University of Korea St. Mary's Hospital [66]The Catholic University of Korea St. Vincent’s Hospital [67]Chung-Ang University Hospital [68]Veterans Health Service Medical Center [69]Keimyung University Dongsan Medical Center [70]Ulsan University Hospital [71]Ajou University Hospital [72]Daegu Catholic University Medical Center [73]Chungbuk National University Hospital [74]The Catholic University of Korea Bucheon St. Mary’s Hospital [75]National Cancer Centre Singapore (NCCS) [76]National University Hospital (NUH) Medical Centre (NUHMC) [77]Semmelweis University [78]Kanazawa University Hospital [79]National Cancer Center East Hospital [80]Tokyo Medical University Hospital [81]Juntendo University Hospital [82]Kanagawa Cancer center [83]Nagoya University Hospital [84]Kinki University Hospital,Faculty of Medicine [85]National Hospital Organization Kinki-Chuo Chest Medical Center [86]Osaka City General Hospital [87]Osaka Medical Center for Cancer and Cardiovascular [88]Kurashiki Central Hospital [89]Hiroshima University Hospital [90]Hiroshima Citizens Hospital [91]National Hospital Organization Yamaguchi [92]Shikoku Cancer Center [93]Kyushu University Hospital [94]University of Occupational and Environmental Health [95]National Kyushu Medical Center [96]Sendai Kousei Hospital [97]Chiba University Hospital [98]岳阳市一人民医院 [99]徐州市中心医院 [100]汕头大学医学院第二附属医院 [101]广西医科大学附属肿瘤医院 [102]宁波市第二医院 [103]天津医科大学总医院 [104]河北医科大学第四医院 [105]湖南省肿瘤医院 [106]首都医科大学宣武医院

研究目的:
在完全切除(IB ≥ 4cm、II或IIIA期)的PD-L1阳性非小细胞肺癌患者中,对照安慰剂,评估MEDI4736(静脉输注一年)作为辅助治疗,对无病生存的影响。

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