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A Study of TAK-994 in Adults With Type 1 and Type 2 Narcolepsy

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研究单位: [1]Takeda [2]Xuanwu Hospital Capital Medical University Beijing,Beijing,China,100053 [3]The First Affiliated Hospital of Jinan University Tianhe,Guangdong,China,510630 [4]The First Hospital of Jilin University Changchun,Jilin,China,130021 [5]Huashan Hospital,Fudan University Shanghai,Shanghai,China,200040 [6]Fakultni nemocnice Hradec Kralove Hradec Kralove,Czechia,50333 [7]Fakultni nemocnice Ostrava Ostrava,Czechia,708 52 [8]Vseobecna fakultni nemocnice v Praze Praha 2,Czechia,128 21

研究目的:
The main aims of the study are: To check for side effects from TAK-994 and check what dose of TAK-994 participants can tolerate. To check what dose range provides adequate relief of narcolepsy symptoms. To check how much TAK-994 stays in the blood of participants, over time. The study will have 4 parts. Participants can only join 1 of the parts. A. Participants with type 1 narcolepsy will take either TAK-994 or placebo tablets for 28 days. A placebo looks just like TAK-994 but will not have any medicine in it. B. Participants with type 1 narcolepsy will take 1 of 3 doses of TAK-994 or placebo tablets for 56 days. C. Participants with type 1 narcolepsy in China only will take TAK-994 or placebo tablets for 56 days. D. Participants with type 2 narcolepsy will take either TAK-994 or placebo tablets for 28 days.

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