研究单位:[1]Xuanwu Hospital,Beijing[2]First Affiliated Hospital of Fujian Medical University[3]Central South University[4]Second Affiliated Hospital,School of Medicine,Zhejiang University[5]Tang-Du Hospital[6]First Affiliated Hospital of Harbin Medical University[7]The First Hospital of Jilin University[8]The First Affiliated Hospital of Dalian Medical University[9]Shanxi Cardiovascular Hospital[10]Qilu Hospital of Shandong University[11]First Affiliated Hospital of Wenzhou Medical University[12]Shandong Provincial Hospital[13]Yantai Yuhuangding Hospital[14]Beijing Tiantan Hospital
研究目的:
This study is a prospective, multi-centre, randomized,controlled trial to compare the efficacy of long-term mild hypothermia with normothermic intensive management in patients with poor-grade aneurysmal subarachnoid hemorrhage.
The primary hypothesis is that the induction of mild hypothermia (maintained at 32-35℃) for at least 5 days would improve the outcome of patients at six months post hemorrhage compared with normothermia.