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High-accuracy wearable detection of freezing of gait in Parkinson's disease based on pseudo-multimodal features.

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机构: [1]Department of Automation Science and Electrical Engineering, Beihang University, China [2]Department of Neurology, Neurobiology and Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing Institute of Geriatrics, China [3]Department of Neurology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China [4]Beijing Key Laboratory of Neuroelectric Stimulation Research and Treatment, Beijing Institute of Neurosurgery, Capital Medical University, China [5]Department of Control and Computer Engineering, Politecnico di Torino, Italy [6]Clinical Center for Parkinson’s Disease, Capital Medical University, China [7]National Clinical Research Center of Geriatric Disorders, Key Laboratory for Neurodegenerative Disease of the Ministry of Education, Beijing Key Laboratory for Parkinson’s Disease, Parkinson Disease Center of Beijing Institute for Brain Disorders, China
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关键词: Freezing of gait Parkinson’s disease Proxy measurement Wearable sensor multimodal information

摘要:
Freezing of gait (FoG) is a serious symptom of Parkinson's disease and prompt detection of FoG is crucial for fall prevention. Although multimodal data combining electroencephalography (EEG) benefit accurate FoG detection, the preparation, acquisition, and analysis of EEG signals are time-consuming and costly, which impedes the application of multimodal information in FoG detection. This work proposes a wearable FoG detection method that merges multimodal information from acceleration and EEG while avoiding the acquisition of real EEG data.A proxy measurement (PM) model based on long-short-term-memory (LSTM) network was proposed to measure EEG features from accelerations, and pseudo-multimodal features, i.e., pseudo-EEG and acceleration, could be extracted using a highly wearable inertial sensor for FoG detection.Based on a self-collected FoG dataset, the performance of different feature combinations were compared in terms of subject-dependent and cross-subject settings. In both settings, pseudo-multimodal features achieved the most promising performance, with a geometric mean of 91.0 ± 5.0% in subject-dependent setting and 91.0 ± 3.5% in cross-subject setting.Our study suggests that wearable FoG detection can be enhanced through leveraging cross-modal information fusion.The new method provides a promising path for multimodal information fusion and the long-term monitoring of FoG in living environments.Copyright © 2022 Elsevier Ltd. All rights reserved.

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出版当年[2021]版:
大类 | 3 区 工程技术
小类 | 2 区 生物学 2 区 数学与计算生物学 3 区 计算机:跨学科应用 3 区 工程:生物医学
最新[2023]版:
大类 | 2 区 医学
小类 | 1 区 生物学 1 区 数学与计算生物学 2 区 计算机:跨学科应用 2 区 工程:生物医学
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出版当年[2020]版:
Q1 BIOLOGY Q1 MATHEMATICAL & COMPUTATIONAL BIOLOGY Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Q2 ENGINEERING, BIOMEDICAL
最新[2023]版:
Q1 BIOLOGY Q1 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Q1 ENGINEERING, BIOMEDICAL Q1 MATHEMATICAL & COMPUTATIONAL BIOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2020版] 出版当年五年平均 出版前一年[2019版] 出版后一年[2021版]

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第一作者机构: [1]Department of Automation Science and Electrical Engineering, Beihang University, China
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通讯机构: [2]Department of Neurology, Neurobiology and Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing Institute of Geriatrics, China [6]Clinical Center for Parkinson’s Disease, Capital Medical University, China [7]National Clinical Research Center of Geriatric Disorders, Key Laboratory for Neurodegenerative Disease of the Ministry of Education, Beijing Key Laboratory for Parkinson’s Disease, Parkinson Disease Center of Beijing Institute for Brain Disorders, China [*1]Department of Neurology, Neurobiology and Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing Institute of Geriatrics, China
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