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Role of optical coherence tomography in pipeline embolization device for the treatment of vertebral-basilar artery dissecting aneurysms

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机构: [1]Capital Med Univ, Xuanwu Hosp, Neurosurg, 45 Changchun St, Beijing, Peoples R China [2]China Int Neurosci Inst, Beijing, Peoples R China [3]Harbin Med Univ Fourth Hosp, Neurosurg, Harbin, Peoples R China [4]Dalian Univ Technol, Software Engn, Dalian, Liaoning, Peoples R China [5]Chinese Acad Sci, Inst Automat, Beijing, Peoples R China [6]Massachusetts Gen Hosp, Neuroendovasc Program, Boston, MA USA [7]Brigham & Womens Hosp, Neuroradiol & Neurointervent, Boston, MA USA
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关键词: Aneurysm Intervention Flow Diverter

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BackgroundVertebral-basilar artery dissecting aneurysms (VADAs) are an uncommon phenomenon in all fields of cerebrovascular disease. The flow diverter (FD) can be used as an endoluminal reconstruction device that promotes neointima formation at the aneurysmal neck and preserves the parent artery. To date, imaging examinations such as CT angiography, MR angiography, and DSA are the main methods used to evaluate the vasculature of patients. However, none of these imaging methods can reveal the situation of neointima formation, which is of great importance in evaluating occlusion of VADAs, especially those treated with a FD. MethodsThree patients were included in the study from August 2018 to January 2019. All patients underwent preprocedural, postprocedural, and follow-up evaluations with high resolution MRI, DSA, and optical coherence tomography (OCT), as well as the formation of intima on the surface of the scaffold at the 6 month follow-up. ResultsPreprocedural, postoperative, and follow-up high resolution MRI, DSA, and OCT of all three cases successfully evaluated occlusion of the VADAs and occurrence of in stent stenosis from different views of intravascular angiography and neointima formation. ConclusionsOCT was feasible and useful to further evaluate VADAs treated with FD from a near pathological perspective, which may contribute toward guiding the duration of antiplatelet medication and early intervention of in stent stenosis.

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出版当年[2023]版:
大类 | 1 区 医学
小类 | 1 区 神经成像 1 区 外科
最新[2023]版:
大类 | 1 区 医学
小类 | 1 区 神经成像 1 区 外科
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Q1 NEUROIMAGING Q1 SURGERY
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Q1 NEUROIMAGING Q1 SURGERY

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第一作者机构: [1]Capital Med Univ, Xuanwu Hosp, Neurosurg, 45 Changchun St, Beijing, Peoples R China [2]China Int Neurosci Inst, Beijing, Peoples R China
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通讯机构: [1]Capital Med Univ, Xuanwu Hosp, Neurosurg, 45 Changchun St, Beijing, Peoples R China [2]China Int Neurosci Inst, Beijing, Peoples R China [*1]Neurosurgery, Xuanwu Hospital, Capital Medical University, No.45 Changchun Street, Xicheng District, Beijing, China
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