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Deep-Learning Model of ResNet Combined with CBAM for Malignant-Benign Pulmonary Nodules Classification on Computed Tomography Images

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机构: [1]Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing 100069, China. [2]Beijing Municipal Key Laboratory of Clinical Epidemiology, Capital Medical University, Beijing 100069, China. [3]Department of Nuclear Medicine, Xuanwu Hospital Capital Medical University, Beijing 100053, China. [4]School of Mathematical Sciences, University College Cork, T12 YN60 Cork, Ireland.
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关键词: lung cancer CT deep learning radiomics machine learning

摘要:
Background and Objectives: Lung cancer remains a leading cause of cancer mortality worldwide. Accurately classifying benign pulmonary nodules and malignant ones is crucial for early diagnosis and improved patient outcomes. The purpose of this study is to explore the deep-learning model of ResNet combined with a convolutional block attention module (CBAM) for the differentiation between benign and malignant lung cancer, based on computed tomography (CT) images, morphological features, and clinical information. Methods and materials: In this study, 8241 CT slices containing pulmonary nodules were retrospectively included. A random sample comprising 20% (n = 1647) of the images was used as the test set, and the remaining data were used as the training set. ResNet combined CBAM (ResNet-CBAM) was used to establish classifiers on the basis of images, morphological features, and clinical information. Nonsubsampled dual-tree complex contourlet transform (NSDTCT) combined with SVM classifier (NSDTCT-SVM) was used as a comparative model. Results: The AUC and the accuracy of the CBAM-ResNet model were 0.940 and 0.867, respectively, in test set when there were only images as inputs. By combining the morphological features and clinical information, CBAM-ResNet shows better performance (AUC: 0.957, accuracy: 0.898). In comparison, a radiomic analysis using NSDTCT-SVM achieved AUC and accuracy values of 0.807 and 0.779, respectively. Conclusions: Our findings demonstrate that deep-learning models, combined with additional information, can enhance the classification performance of pulmonary nodules. This model can assist clinicians in accurately diagnosing pulmonary nodules in clinical practice.

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出版当年[2022]版:
大类 | 4 区 医学
小类 | 3 区 医学:内科
最新[2023]版:
大类 | 4 区 医学
小类 | 3 区 医学:内科
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出版当年[2021]版:
Q3 MEDICINE, GENERAL & INTERNAL
最新[2023]版:
Q1 MEDICINE, GENERAL & INTERNAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2021版] 出版当年五年平均 出版前一年[2020版] 出版后一年[2022版]

第一作者:
第一作者机构: [1]Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing 100069, China. [2]Beijing Municipal Key Laboratory of Clinical Epidemiology, Capital Medical University, Beijing 100069, China.
通讯作者:
通讯机构: [1]Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing 100069, China. [2]Beijing Municipal Key Laboratory of Clinical Epidemiology, Capital Medical University, Beijing 100069, China.
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