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Short-term surgical outcomes of spontaneous intracerebral hemorrhage in China from 2019 to 2021: a retrospective cohort study

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机构: [1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing 100053, China. [2]General Office of the Stroke Prevention Project Committee, National Health Commission of the People's Republic of China, Beijing, China. [3]National Center for Neurological Disorders, Beijing 100053, China. [4]Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, Beijing 100069, China. [5]Medical Library of Xuanwu Hospital, Xuanwu Hospital, Capital Medical University, Beijing, China. [6]School of Public Health, Peking University, Beijing, China. [7]Beijing Municipal Geriatric Medical Research Center, Beijing 100053, China.
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关键词: Intracerebral hemorrhage Short-term outcomes Open craniotomy Cranial puncture Decompressive craniectomy Endoscopic evacuation Propensity score matching

摘要:
China has the highest prevalence of spontaneous intracerebral hemorrhage (sICH) worldwide. To date, no national-level report has revealed sICH surgical performance. We aimed to investigate the current status and short-term outcomes of patients who underwent surgical treatment for sICH between 2019 and 2021.Data from 7451 patients undergoing sICH surgical treatment in China between 2019 and 2021, including demographic information, disease severity, surgical treatments for sICH, complications, and follow-up information, were retrieved from the Bigdata Observatory Platform for Stroke of China. Propensity score matching (PSM) was applied to balance the baseline characteristics. The surgical treatment performance on 3-month mortality and functional outcome were then explored by regression analysis. The influence of stroke center level and region on surgical performance was then explored.The numbers of sICH patients undergoing open craniotomy (OC), cranial puncture (CP), decompressive craniectomy (DC) and endoscopic evacuation (EE) were 2404 (32.3%), 3030 (40.7%), 1700 (22.8%) and 317 (4.3%), respectively. The 3-month mortality rate was 20.2%. Among the surviving patients, the 3-month poor functional prognosis (mRS 3-5) rate was 46.5%. After PSM, regression analysis showed that DC was associated with a higher mortality risk (OR = 1.31, 95% CI 1.06-1.61) than OC. CP was associated with a lower risk of poor mRS scores than OC (OR = 0.84, 95% CI 0.70-1.01), especially in stroke prevention centers and specific regions.Outcome improvements in Chinese sICH patients undergoing surgical treatment are worth expecting. Inconsistent surgical performance, especially functional outcome, affected by inhomogeneity of the hospital should be addressed.This work was supported by the Beijing Hospitals Authority Youth Programme (QML20230804), the National Natural Science Foundation of China (81701796, 82030037, 81871009), Capital Health Research and Development of Special Fund (2020-2Z-2019), Science and Technology Innovation 2030-Major Project (2021ZD0201801), and the Translational and Application Project of Brain-inspired and Network Neuroscience on Brain Disorders (11000022T000000444685).© 2023 The Author(s).

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出版当年[2022]版:
大类 | 2 区 医学
小类 | 2 区 卫生保健与服务 2 区 公共卫生、环境卫生与职业卫生
最新[2023]版:
大类 | 1 区 医学
小类 | 1 区 卫生保健与服务 1 区 公共卫生、环境卫生与职业卫生
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出版当年[2021]版:
Q1 HEALTH CARE SCIENCES & SERVICES Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
最新[2023]版:
Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Q1 HEALTH CARE SCIENCES & SERVICES

影响因子: 最新[2023版] 最新五年平均 出版当年[2021版] 出版当年五年平均 出版前一年[2020版] 出版后一年[2022版]

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第一作者机构: [1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing 100053, China.
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通讯机构: [1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing 100053, China. [2]General Office of the Stroke Prevention Project Committee, National Health Commission of the People's Republic of China, Beijing, China. [3]National Center for Neurological Disorders, Beijing 100053, China. [6]School of Public Health, Peking University, Beijing, China. [7]Beijing Municipal Geriatric Medical Research Center, Beijing 100053, China.
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