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Clinical Observation of Various Types of Idiopathic Hypertrophic Cranial Pachymeningitis

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机构: [1]Xuanwu Hospital, Capital Medical University, Skull Base Surgery Center and Department of Otorhinolaryngology-Head and Neck Surgery, Beijing, China. [2]Xuanwu Hospital, Capital Medical University, Department of Rheumatism and Immunity, Beijing, China. [3]Xuanwu Hospital, Capital Medical University, Department of Radiology, Beijing, China. [4]Xuanwu Hospital, Capital Medical University, Department of Pathology, Beijing, China. [5]Xuanwu Hospital, Capital Medical University, Skull Base Surgery Center and Department of Otorhinolaryngology-Head and Neck Surgery, Beijing, China.
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关键词: Clinical Observation Idiopathic Hypertrophic Cranial Pachymeningitis Fibroblasts Corticosteroid

摘要:
To assist doctors in making better treatment decisions and improve patient prognosis, it is important to determine which therapy modalities are suitable for various forms of idiopathic hypertrophic cranial pachymeningitis (IHCP). All cases were received from the hospital medical record system, and some follow-up information was gathered through telephone follow-up. A total of 26 patients, 14 men and 12 women, with ages ranging from 20 to 73 and a mean of 47.42 years, were included in the research. Regular types were less likely to recur than irregular and nodular types, focal types were less likely to recur than diffuse types , and corticosteroid-refractory types were more likely to recur than corticosteroid-sensitive types. The extent and shape of the lesion and susceptibility to corticosteroids are potential factors that could influence recurrence. Futhermore, this paper also proposes the fibroblasts as a new therapeutic target which may improve the quality of prognostic survival of patients.Copyright © 2023. Published by Elsevier Inc.

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出版当年[2023]版:
大类 | 4 区 医学
小类 | 4 区 临床神经病学 4 区 外科
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 临床神经病学 4 区 外科
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出版当年[2022]版:
Q3 SURGERY Q4 CLINICAL NEUROLOGY
最新[2023]版:
Q2 SURGERY Q3 CLINICAL NEUROLOGY

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第一作者机构: [1]Xuanwu Hospital, Capital Medical University, Skull Base Surgery Center and Department of Otorhinolaryngology-Head and Neck Surgery, Beijing, China.
通讯作者:
通讯机构: [5]Xuanwu Hospital, Capital Medical University, Skull Base Surgery Center and Department of Otorhinolaryngology-Head and Neck Surgery, Beijing, China. [*1]No.45 Changchun Street, Xicheng District, Beijing
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