机构：[1]Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Beijing 100053, China.神经科系统神经外科功能神经外科首都医科大学宣武医院[2]Department of Neurology, The second Clinical Medical College of Guizhou University of traditional Chinese Medicine, Guiyang 550001, Guizhou, China.
BackgroundSurgical treatment for patients with adult-onset Rasmussen's encephalitis (A-RE) is rarely reported. We investigated the clinical and surgical features of two patients with A-RE who underwent functional hemispherectomy.Case presentationThe data of clinical manifestations, neuroimaging, surgical treatment and surgical outcomes of two patients with A-RE was reviewed. The two patients initially presented with recurrent partial seizures or secondly generalized tonic clonic seizures. Gradually, the patients showed unilateral limb paralysis as well as chronic focal epileptic status. Both patients underwent functional hemispherectomy and achieved seizure freedom in the follow-up. The contralateral neurological deficits improved gradually after rehabilitation and were acceptable for the self-care of daily living. The living quality improved prominently after surgery.ConclusionsDespite the risk of hemiplegia, functional hemispherectomy may be a choice for patients with A-RE for favorable seizure control and improved quality of life in selected patients.
基金：
National Natural Science Foundation of China
(Grant No. 81771395).
第一作者机构：[1]Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Beijing 100053, China.[2]Department of Neurology, The second Clinical Medical College of Guizhou University of traditional Chinese Medicine, Guiyang 550001, Guizhou, China.
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Xue Hong,Xu Cuiping,Zhou Xiaoxia,et al.Functional hemispherectomy for patients with adult-onset Rasmussen's encephalitis[J].ACTA EPILEPTOLOGICA.2021,3(1):doi:10.1186/s42494-021-00045-1.
APA：
Xue, Hong,Xu, Cuiping,Zhou, Xiaoxia,Ni, Duanyu,Wang, Xueyuan&Yu, Tao.(2021).Functional hemispherectomy for patients with adult-onset Rasmussen's encephalitis.ACTA EPILEPTOLOGICA,3,(1)
MLA：
Xue, Hong,et al."Functional hemispherectomy for patients with adult-onset Rasmussen's encephalitis".ACTA EPILEPTOLOGICA 3..1(2021)
