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The link between sleep duration and stroke risk

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机构: [1]Luhe Institute of Neuroscience, Capital Medical University [2]Department of Neurology, Beijing Luhe Hospital, Capital Medical University, 5 Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing,China [3]Department of Neurosurgery, Wayne State University School of Medicine [4]Department of Biomedical Engineering, Wayne State University, Detroit, MI, USA [5]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China
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关键词: Cardiovascular health and neurovascular integrity excessive and insufficient sleep Mendelian randomization studies observational

摘要:
In this review paper, we explore the complex relationship between sleep duration and stroke risk, outlining the association of both insufficient sleep and excessive sleep with an increased risk of cerebrovascular diseases. We explore a U-shaped relationship between sleep duration and cardiovascular outcomes, including stroke. Our review explores findings from cohort studies, meta-analyses, and Mendelian randomization studies, highlighting the nuanced findings and identifying gaps in the current literature. We discussed the direct and indirect effects of sleep duration on stroke risk, considering factors such as atherosclerosis, atrial fibrillation, hypertension, and hyperlipidemia. We also discuss the methodological challenges inherent in current studies, such as the reliance on self-reported sleep measures and the need for more objective and comprehensive assessments. The paper emphasizes the importance of recognizing individual variations in optimal sleep duration and the potential confounding effects of sleep quality and other sleep-related disorders on stroke risk. Furthermore, we explore the potential mechanisms by which sleep duration may influence endothelial function, oxidative stress, and vascular compliance, suggesting areas for future investigation. The paper makes a compelling case for the inclusion of sleep duration as a key factor in stroke prevention strategies, recommending that healthcare professionals proactively assess and manage sleep patterns to mitigate stroke risk.

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出版当年[2025]版:
大类 | 4 区 医学
小类 | 4 区 临床神经病学 4 区 神经科学
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 临床神经病学 4 区 神经科学
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出版当年[2023]版:
Q3 CLINICAL NEUROLOGY Q3 NEUROSCIENCES
最新[2023]版:
Q3 CLINICAL NEUROLOGY Q3 NEUROSCIENCES

影响因子: 最新[2023版] 最新五年平均 出版当年[2023版] 出版当年五年平均 出版前一年[2022版]

第一作者:
第一作者机构: [1]Luhe Institute of Neuroscience, Capital Medical University [2]Department of Neurology, Beijing Luhe Hospital, Capital Medical University, 5 Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing,China
通讯作者:
通讯机构: [1]Luhe Institute of Neuroscience, Capital Medical University [2]Department of Neurology, Beijing Luhe Hospital, Capital Medical University, 5 Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing,China [3]Department of Neurosurgery, Wayne State University School of Medicine
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