机构：[1]Nanjing General Hospital of Nanjing Military Command, No.305 Zhongshan East Road, Nanjing 210002, China.[2]Department of emergency medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.[3]Henan Provincial People’s Hospital, Zhengzhou, China.[4]Zhongshan People’s Hospital, Zhongshan, China.[5]Shandong University Qilu Hospital, Jinan, China.[6]Changzhou No.2 People’s Hospital affiliated to Nanjing Medical University, Nanjing, China.[7]Jilin University First Hospital, Changchun, China.[8]Xiangya Hospital Central South University, Changsha, China.[9]Guizhou Medical University affiliated hospital, Guiyang, China.[10]Wuxi People’s Hospital, Wuxi, China.[11]Hubei Provincial People’s Hospital, Wuhan, China.[12]Tai’an Central Hospital, Tai’an, China.[13]First Affiliated Hospital of Nanchang University, Nanchang, China.[14]Third Military Medical University Daping Hospital, Chongqing, China.[15]China Medical University Second Affiliated Hospital, Shenyang, China.[16]Guangzhou Medical University First Affiliated Hospital, Guangzhou, China.[17]Sichuan Provincial People’s Hospital, Chengdu, China.四川省人民医院[18]Qingdao Municipal Hospital Group, Qingdao, China.[19]Jining First People’s Hospital, Jining, China.[20]Guangzhou First Municipal People’s Hospital, Guangzhou, China.[21]Xiehe Affiliated Hospital of Fujian Medical University, Fuzhou, China.[22]Dazhou Central Hospital, Dazhou, China.[23]Inner Mongolia People’s Hospital, Huhehaote, China.[24]Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Hangzhou, China.[25]Qindao University Medical College Affiliated Yantai Yuhuangding Hospital, Qingdao, China.[26]Tianjing People’s Hospital, Tianjin, China.[27]Tianjing First Central Hospital, Tianjin, China.[28]Tangshan Gongren Hospital, Tangshan, China.[29]Southern Medical University Zhujiang Hospital, Guangzhou, China.[30]North China University of Science and Technology Affiliated Hospital, Tangshan, China.[31]Dalian Central Hospital, Dalian, China.[32]Peking University Third Hospital, Beijing, China.[33]Anhui Medical University Second Affiliated Hospital, Hefei, China.[34]Wenzhou Medical University First Affiliated Hospital, Wenzhou, China.[35]Shanxi Provincial People’s Hospital, Taiyuan, China.[36]Guangzhou Medical University Second Affiliated Hospital, Guangzhou, China.[37]Second Affiliated Hospital of Dalian Medical University, Dalian, China.[38]Zhengzhou University First Affiliated Hospital, Zhengzhou, China.[39]First People’s Hospital of Kunming, Kunming, China.[40]Union Hospital Affiliated to Tongji Medical College of Huanzhong University of Science and Technology, Wuhan, China.[41]Xinjiang Medical University Affiliated First Hospital, Wulumuqi, China.[42]Chengdu University of Traditional Chinese Medicine Affiliated Hospital, Chengdu, China.[43]First Affiliated Hospital of Anhui Medical University, Hefei, China.[44]Yichang Central People’s Hospital, Yichang, China.[45]Suzhou Municipal Hospital, Suzhou, China.[46]Jining Medical College Affiliated Hospital, Jining, China.[47]First Affiliated Hospital of Soochow University, Suzhou, China.[48]Qindao University Medical College Affiliated Hospital, Qindao, China.[49]Central South University Third Xiangya Hospital, Changsha, China.[50]401 Military Hospital of China, Qindao, China.[51]Changsha Central Hospital, Changsha, China.[52]Yijishan Hospital of Wannan Medical College, Wuhu, China.[53]Shanxi Medical University First Affiliated Hospital, Taiyuan, China.[54]Kuming Medical University First Affiliated Hospital, Kuming, China.[55]Hebei Medical University Third Affiliated Hospital, Shijiazhuang, China.[56]First Affiliated Hospital of Fujian Medical University, Fuzhou, China.[57]Zibo Central Hospital, Zibo, China.[58]First People’s Hospital of Yichang, Yichang, China.[59]Wuhan University Zhongnan Hospital, Wuhan, China.[60]Wenzhou Medical University Second Affiliated Hospital, Wenzhou, China.[61]Shantou University Medical College First Affiliated Hospital, Shantou, China.[62]Zhongnan University Xiangya Second Hospital, Changsha, China.[63]Yunnan Second People’s Hospital, Kunming, China.[64]Yancheng First People’s Hospital, Yancheng, China.[65]First People’s Hospital of Foshan, Foshan, China.[66]Chongqing Medical University First Affiliated Hospital, Chongqing, China.[67]Xi’an Jiao Tong University First Affiliated Hospital, Xi’an, China.[68]Beijing Wujing General Hospital, Beijing, China.[69]Shenzhen People’s Hospital, Shenzhen, China.[70]Shanxi Dayi Hospital of Shanxi Academy of Medical Science, Taiyuan, China.[71]254 Military Hospital of China, Tianjin, China.[72]Qingdao University Affiliated Hospital, Qingdao, China.[73]Linhai First People’s Hospital, Linhai, China.[74]Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.[75]First Affiliated Hospital of Dalian Medical University, Dalian, China.[76]Beijing Chaoyang Hospital, Beijing, China.[77]Chongqing Medical University Second Affiliated Hospital, Chongqing, China.[78]People’s Hospital of Yuxi City, Yuxi, China.[79]Shijitan Hospital of Capital Medical University, Beijing, China.[80]Shenzhen Nanshan People’s Hospital, Shenzhen, China.[81]Affiliated Hospital of Inner Mongolia Medical College, Huhehaote, China.[82]Benq Hospital, Nanjing, China.[83]Luhe Hospital, Beijing, China.[84]Beijing Jingmei Group General Hospital, Beijing, China.[85]Jiangxi Provincial People’s Hospital, Nanchang, China.[86]Jinan University First Affiliated Hospital, Jinan, China.[87]General Hospital of Rocket Army, Beijing, China.[88]Hebei Medical University Second Affiliated Hospital, Shijiazhuang, China.[89]Binzhou Medical College Affiliated Hospital, Binzhou, China.[90]Chinese PLA General Hospital, Beijing, China.[91]Yantai Mountain Hospital, Yantai, China.[92]Tianjing Hospital of ITCWM Nankai Hospital, Tianjing, China.[93]Hunan Provincial People’s Hospital, Changsha, China.[94]People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.[95]Sun Yat-sen University Sixth Affiliated Hospital, Guangzhou, China.[96]China Academy of Chinese Medical Sciences Xiyuan Hospital, Beijing, China.[97]Wuhan General Hospital of Guangzhou Military Region, Wuhan, China.[98]First People’s Hospital of Yunnan, Kunming, China.[99]Xinjiang Military General Hospital, Wulumuqi, China.[100]Miyun Hospital of Beijing, Beijing, China.[101]Luoyang Central Hospital, Luoyang, China.[102]Huairou First Hospital of Beijing, Beijing, China.[103]Military General Hospital of Beijing PLA, Beijing, China.[104]Guangdong Provincial People’s Hospital, Guangzhou, China.[105]Guangdong Second TCM Hospital, Guangzhou, China.[106]Beijing Hospital of TCM, Beijing, China.[107]Anhui Provincial Hospital, Hefei, China.[108]Shenyang First People’s Hospital, Shenyang, China.[109]Guangzhou Military General Hospital, Guangzhou, China.[110]Sun Yat-sen University First Affiliated Hospital, Guangzhou, China.[111]Tianjing Cancer Hospital, Tianjing, China.[112]Shanxi Cancer Hospital, Taiyuan, China.[113]Nanchang University Second Affiliated Hospital, Nanchang, China.[114]Beijing University of Chinese Medicine Affiliated Dongfang Hospital, Beijing, China.[115]Shenzhen Second People’s Hospital, Shenzhen, China.[116]Chendu Fifth People’s Hospital, Chendu, China.
Background: There is a lack of large-scale epidemiological data on the clinical practice of enteral nutrition (EN) feeding in China. This study aimed to provide such data on Chinese hospitals and to investigate factors associated with EN delivery. Methods: This cross-sectional study was launched in 118 intensive care units (ICUs) of 116 mainland hospitals and conducted on April 26, 2017. At 00:00 on April 26, all patients in these ICUs were included. Demographic and clinical variables of patients on April 25 were obtained. The dates of hospitalization, ICU admission and nutrition initiation were reviewed. The outcome status 28 days after the day of investigation was obtained. Results: A total of 1953 patients were included for analysis, including 1483 survivors and 312 nonsurvivors. The median study day was day 7 (IQR 2-19 days) after ICU entry. The proportions of subjects starting EN within 24, 48 arid 72 h after ICU entry was 24.8% (84/352), 32.7% (150/459) and 40.0% (200/541), respectively. The proportion of subjects receiving > 80% estimated energy target within 24, 48, 72 h and 7 days after ICU entry was 10.5% (37/352), 10.9% (50/459), 11.8% (64/541) and 17.8% (162/910), respectively. Using acute gastrointestinal injury (AGI) 1 as the reference in a Cox model, patients with AGI 2-3 were associated with reduced likelihood of EN initiation (HR 0.46, 95% CI 0.353-0.599; p < 0.001). AGI 4 was significantly associated with lower hazard of EN administration (HR 0.056; 95% CI 0.008-0.398; p = 0.004). In a linear regression model, greater Sequential Organ Failure Assessment scores (coefficient - 0.002, 95% CI - 0.008 to - 0.001; p = 0.024) and male gender (coefficient - 0.144, 95% CI - 0.203 to - 0. 085; p < 0.001) were found to be associated with lower EN proportion. As compared with AGI 1, AGI 2-3 was associated with lower EN proportion (coefficient - 0206, 95% CI - 0.273 to - 0.139; p < 0.001). Conclusions: The study showed that EN delivery was suboptimal in Chinese ICUs. More attention should be paid to EN use in the early days after ICU admission.
基金：
This study was funded by The Standard Treatment to Key Diseases of Jiangsu Social Development Programme (BE2015685).
第一作者机构：[1]Nanjing General Hospital of Nanjing Military Command, No.305 Zhongshan East Road, Nanjing 210002, China.
通讯作者：
通讯机构：[1]Nanjing General Hospital of Nanjing Military Command, No.305 Zhongshan East Road, Nanjing 210002, China.
推荐引用方式(GB/T 7714)：
Xing J (Xing Juan)[ 1 ],Zhang ZH (Zhang Zhongheng)[ 2 ],Ke L (Ke Lu)[ 1 ],et al.Enteral nutrition feeding in Chinese intensive care units: a cross-sectional study involving 116 hospitals[J].CRITICAL CARE.2018,22(1):229.doi:10.1186/s13054-018-2159-x.
APA：
Xing, J (Xing, Juan)[ 1 ],Zhang, ZH (Zhang, Zhongheng)[ 2 ],Ke, L (Ke, Lu)[ 1 ],Zhou, J (Zhou, Jing)[ 1 ],Qin, BY (Qin, Bingyu)[ 3 ]...&Li, WQ (Li, Weiqin)[ 1 ].(2018).Enteral nutrition feeding in Chinese intensive care units: a cross-sectional study involving 116 hospitals.CRITICAL CARE,22,(1)
MLA：
Xing, J (Xing, Juan)[ 1 ],et al."Enteral nutrition feeding in Chinese intensive care units: a cross-sectional study involving 116 hospitals".CRITICAL CARE 22..1(2018):229
医学