机构：[1]Department of Neurobiology, Neurology and Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing Institute of Geriatrics, Beijing, China神经内科老年医学科[2]Clinical Center for Parkinson’s Disease, Capital Medical University, Beijing, China[3]Key Laboratory for Neurodegenerative Disease of the Ministry of Education, Beijing Key Laboratory for Parkinson’s Disease, Parkinson Disease Center of Beijing Institute for Brain Disorders, Beijing, China[4]National Clinical Research Center for Geriatric Disorders, Beijing, China
Objectives We sought to assess associations of postural tremor with gait and balance impairments among community-dwelling older people in both cross-sectional and longitudinal analyses. Design A prospective cohort study. Setting Communities in Beijing, China. Participants This study included 7075 individuals aged 55 years or older. Measurements Postural tremor was assessed using a two-step method (tremor screening followed by a confirmation examination of positive cases) at baseline. Gait and balance performances were measured with the Tinetti Mobility Test at baseline and 1 year later. Results At baseline, 45 (24.7%) of 182 tremor cases vs 663 (9.6%) of 6893 controls had gait and balance impairments. At 1-year follow-up, 19 (21.1%) of 90 tremor cases vs 416 (9.8%) of 4262 controls experienced a rapid decline in gait and balance performance. After controlling for potential confounders, postural tremor was associated with gait and balance impairments at baseline (odds ratio [OR] = 1.77; 95% confidence interval [CI] = 1.20-2.62; p = .004) and a rapid decline in gait and balance performance at 1-year follow-up (OR = 1.99; 95% CI = 1.17-3.39; p = .01). Conclusion In this population-based cohort study, we found postural tremor was associated with gait and balance impairments among community-dwelling older people in both cross-sectional and longitudinal analyses. Our findings suggest that motor function should be routinely evaluated and monitored in older people with postural tremor. J Am Geriatr Soc 67:799-803, 2019.
第一作者机构：[1]Department of Neurobiology, Neurology and Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing Institute of Geriatrics, Beijing, China
通讯作者：
通讯机构：[1]Department of Neurobiology, Neurology and Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing Institute of Geriatrics, Beijing, China[*1]Department of Neurobiology, Neurology and Geriatrics, Xuanwu Hospital of Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China.[2]Clinical Center for Parkinson’s Disease, Capital Medical University, Beijing, China[3]Key Laboratory for Neurodegenerative Disease of the Ministry of Education, Beijing Key Laboratory for Parkinson’s Disease, Parkinson Disease Center of Beijing Institute for Brain Disorders, Beijing, China[4]National Clinical Research Center for Geriatric Disorders, Beijing, China
推荐引用方式(GB/T 7714)：
Xu Xitong,Chen Jie,Chen Meijie,et al.Postural Tremor Is Associated with Gait and Balance Impairments in Community-Dwelling Older People[J].JOURNAL OF THE AMERICAN GERIATRICS SOCIETY.2019,67(4):799-803.doi:10.1111/jgs.15778.
APA：
Xu, Xitong,Chen, Jie,Chen, Meijie,Gu, Zhuqin,Ji, Shaozhen...&Chan, Piu.(2019).Postural Tremor Is Associated with Gait and Balance Impairments in Community-Dwelling Older People.JOURNAL OF THE AMERICAN GERIATRICS SOCIETY,67,(4)
MLA：
Xu, Xitong,et al."Postural Tremor Is Associated with Gait and Balance Impairments in Community-Dwelling Older People".JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 67..4(2019):799-803
医学