机构：[1]Department of Neurobiology, Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University, No. 45 Changchun St., Xicheng District, Beijing 100053, China老年医学科首都医科大学宣武医院[2]Department of Geriatrics, Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing 100053, China老年医学科首都医科大学宣武医院[3]Department of Neurology, Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing 100053, China神经内科老年医学科首都医科大学宣武医院[4]Department of Rheumatology, Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing 100053, China老年医学科首都医科大学宣武医院[5]Department of Endocrinology, Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing 100053, China内分泌科老年医学科首都医科大学宣武医院[6]Key Laboratory on Neurodegenerative Disease of Ministry of Education, and Beijing Key Laboratory for Parkinson’s Disease, Parkinson’s Disease Center of Beijing Institute for Brain Disorders, Beijing 100053, China
AimObesity is found to be associated with frailty. Body mass index (BMI) and waist circumference (WC) are the commonly used measures for obesity, the former is more closely related to general obesity and body weight; the latter can more accurately reflect abdominal obesity and is more closely associated with metabolic disorders. In this study, we intend to study the relationship between frailty, BMI and WC among older people.MethodsData were derived from the Beijing Longitudinal Study on Aging II Cohort, which included 6320 people 65years or older from three urban districts in Beijing. A Frailty Index derived from 33 items was developed according to Rockwood's cumulative deficits method. A Frailty Index0.25 was used as the cut-off criteria. BMI was classified as underweight, normal, overweight, or obese (<18.5, 18.5-<24.0, 24.0-27.9, 28.0kg/m(2), respectively). High WC was defined as WC85cm in men and 80cm in women.ResultsPeople with a larger BMI (28.0kg/m(2), 22.6%) or a larger WC (18.5%) were more likely to be frail. People with normal BMI and overweight people do not suffer from higher prevalence for frailty. In comparison with individuals with normal BMI (18.5-<24.0kg/m(2)) and normal WC (<85cm in men, <80cm in women), the risk of frailty was higher among individuals who have normal BMI and large WC (odds ratio 1.68; 95% CI 1.33-2.12), have overweight and large WC (odds ratio 1.58; 95% CI 1.23-1.96), or have obesity and large WC (odds ratio 2.28; 95% CI 1.79-2.89). In people with normal WC, only those who are underweight have a higher risk for frailty (odds ratio 1.65, 95% CI 1.08-2.52). In comparison with BMI, the relation of WC with the risk for frailty was much closer.ConclusionsAbdominal obesity is more closely associated with incidence of frailty than general obesity in the elderly. Older adults with large waist circumference are more likely to be frail. Frailty in the elderly might be more closely related to metabolic disorders. WC might be a better measurement to detect frailty than BMI, given its relationship with metabolic disorders.
基金：
Beijing Municipal Commission on Science and Technology [D07050701130000, D07050701130701]; Ministry of Health of China [201002011]; Ministry of Science and Technology of China [2012AA02A514, 0S2012GR0150, 2012ZX09303-005]
第一作者机构：[2]Department of Geriatrics, Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing 100053, China[4]Department of Rheumatology, Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing 100053, China
通讯作者：
通讯机构：[1]Department of Neurobiology, Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University, No. 45 Changchun St., Xicheng District, Beijing 100053, China[2]Department of Geriatrics, Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing 100053, China[3]Department of Neurology, Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing 100053, China[4]Department of Rheumatology, Beijing Institute of Geriatrics, Xuanwu Hospital of Capital Medical University, Beijing 100053, China[6]Key Laboratory on Neurodegenerative Disease of Ministry of Education, and Beijing Key Laboratory for Parkinson’s Disease, Parkinson’s Disease Center of Beijing Institute for Brain Disorders, Beijing 100053, China
推荐引用方式(GB/T 7714)：
Qiuju Liao,Zheng Zheng,Shuangling Xiu,et al.Waist circumference is a better predictor of risk for frailty than BMI in the community-dwelling elderly in Beijing[J].AGING CLINICAL AND EXPERIMENTAL RESEARCH.2018,30(11):1319-1325.doi:10.1007/s40520-018-0933-x.
APA：
Qiuju Liao,Zheng Zheng,Shuangling Xiu&Piu Chan.(2018).Waist circumference is a better predictor of risk for frailty than BMI in the community-dwelling elderly in Beijing.AGING CLINICAL AND EXPERIMENTAL RESEARCH,30,(11)
MLA：
Qiuju Liao,et al."Waist circumference is a better predictor of risk for frailty than BMI in the community-dwelling elderly in Beijing".AGING CLINICAL AND EXPERIMENTAL RESEARCH 30..11(2018):1319-1325
