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Intracranial Rosai-Dorfman Disease Involving the Cavernous Sinus: A Case Report and Review of the Literature

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收录情况： ◇ SCIE

作者：

机构： [1]Department of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang [2]Department of Neurosurgery, Xiamen Humanity Hospital, Xiamen [3]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China

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关键词： Central nervous system Cavernous sinus Rosai-Dorfman disease Sinus histiocytosis with massive lymphadenopathy Treatment

摘要：

BACKGROUND: Rosai-Dorfman disease (RDD), also called sinus histiocytosis with massive lymphadenopathy, is an idiopathic, non-neoplastic, lymphoproliferative disorder. Histologically, the disease is characterized by emperipolesis and S-100 immunoreactivity. RDD usually presents with massive painless cervical lymphadenopathy, with only 5% of cases affecting the central nervous system. CASE DESCRIPTION: We report the case of a 46-year-old woman with isolated RDD of the left cavernous sinus with left facial numbness and weakness of the left masticatory muscle. The patient was successfully treated by total resection without recurrence found at the 65-month follow-up examination. CONCLUSIONS: Central nervous system RDD is a diagnostic challenge pre-operatively depending on the radiologic findings. Immunohistochemical confirmation is indispensable for the definite diagnosis. Total resection remains the most effective treatment to date. Adjuvant treatment such as chemotherapy, radiotherapy, and steroids can be administrated in cases of incomplete resection, recurrence, or multiple foci.

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出版当年[2017]版：

大类 | 3 区医学

小类 | 3 区临床神经病学 3 区外科

最新[2023]版：

大类 | 4 区医学

小类 | 4 区临床神经病学 4 区外科

JCR分区：

出版当年[2016]版：

Q2 CLINICAL NEUROLOGY Q2 SURGERY

最新[2023]版：

Q2 SURGERY Q3 CLINICAL NEUROLOGY

影响因子： 1.9 最新[2023版] 2 最新五年平均 2.592 出版当年[2016版] 2.795 出版当年五年平均 2.685 出版前一年[2015版] 1.924 出版后一年[2017版]

第一作者：

第一作者机构： [1]Department of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang

通讯作者：

通讯机构： [3]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China

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