机构:[1]Beijing Geriatric Healthcare Center, Xuanwu Hospital, Capital Medical University, Beijing Institute of Geriatrics, Key Laboratory on Neurodegenerative Disease of Ministry of Education, Beijing 100053, China老年医学科首都医科大学宣武医院[2]Department of Geriatrics, Xuanwu Hospital, Capital Medical University, China National Clinical Research Center for Geriatric Medicine, Beijing 100053, China老年医学科首都医科大学宣武医院[3]Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China[4]Department of Neurology and Neurobiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China神经内科首都医科大学宣武医院
Frailty, which involves low physical activity (PA), is as a well-established factor of increased risk of hospitalization, disability, and mortality. To date, there are no specific tools to assess PA among Chinese elderly. As part of the Beijing Longitudinal Study of Aging (BLSA), we aimed to develop the BLSA Leisure-Time Physical Activity Questionnaire (BLSA-PAQ) and assess its prediction of mortality. Longitudinal study. Community. 1810 Chinese older adults completed the BLSA-PAQ questionnaire. BLSA-PAQ questionnaire containing four items: walking, outdoor chores, low-intensity exercise, and moderate-intensity exercise. Physical function was assessed through the balance test, chair-stand test, and the activities of daily living (ADL), and instrumental activities of daily living (IADL). Frailty was evaluated using a modified frailty phenotype and frailty index. The following equation was obtained based on the 8-year mortality for the four BLSA-PAQ components: BLSA-PAQ index (BLSA-PAQ total score) = Walking score + Outdoor chores score + 2 x (low-intensity exercise score) + 3 x (moderate-intensity exercise score). The BLSA-PAQ index decreased with age, and was negatively related to modified frailty phenotype score and frailty index. Low PA and pre-low PA statuses were associated with poorer results in the balance and chair-stand tests, ADL dependency, IADL dependency, and frailty. After adjusting for age and gender, the 8-year mortality HRs were 1.453 (95% CI, 1.166-1.811) and 2.358 (95% CI, 1.856-2.995) for low PA and pre-low PA, respectively. Low PA defined by the BLSA-PAQ index was associated with frailty, disability, worse physical function, and higher mortality. The BLSA-PAQ seems to be a reliable tool to measure PA in Chinese older adults. Further studies are needed to confirm these findings and validate the use of the BLSA-PAQ for frailty assessments of older adults.
基金:
This work was supported by United Nations Population Fund (CPR/90/P23), and the Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support (ZYLX201706).
第一作者机构:[1]Beijing Geriatric Healthcare Center, Xuanwu Hospital, Capital Medical University, Beijing Institute of Geriatrics, Key Laboratory on Neurodegenerative Disease of Ministry of Education, Beijing 100053, China[2]Department of Geriatrics, Xuanwu Hospital, Capital Medical University, China National Clinical Research Center for Geriatric Medicine, Beijing 100053, China
共同第一作者:
通讯作者:
通讯机构:[*1]Beijing Geriatric Healthcare Center, Xuanwu Hospital, Capital Medical University, #45 Changchun Street, Xicheng District, Beijing 100053, China
推荐引用方式(GB/T 7714):
L. MA,J. WANG,Z. TANG,et al.Simple Physical Activity Index Predicts Prognosis in Older Adults: Beijing Longitudinal Study of Aging[J].JOURNAL OF NUTRITION HEALTH & AGING.2018,22(7):854-860.doi:10.1007/s12603-018-1037-1.
APA:
L. MA,J. WANG,Z. TANG&P. CHAN.(2018).Simple Physical Activity Index Predicts Prognosis in Older Adults: Beijing Longitudinal Study of Aging.JOURNAL OF NUTRITION HEALTH & AGING,22,(7)
MLA:
L. MA,et al."Simple Physical Activity Index Predicts Prognosis in Older Adults: Beijing Longitudinal Study of Aging".JOURNAL OF NUTRITION HEALTH & AGING 22..7(2018):854-860