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Improvement of chronic hepatitis B by iron chelation therapy in a patient with iron overload: A case report

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收录情况： ◇ SCIE

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机构： [a]Department of Hematology, Xuanwu Hospital, Capital Medical University, Beijing, P. R. China. [b]Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, P. R. China.

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关键词： hepatitis B virus iron chelation therapy iron overload

摘要：

Rationale:This report describes seroconversion of hepatitis B surface antigen (HBsAg) in a patient with marked iron overload caused by chronic hepatitis B (CHB) after receiving iron chelation therapy and discusses the role of iron chelation therapy in CHB.Patient concerns:Increased serum ferritin level for 2 months.Diagnosis:Secondary iron overload and CHB.Intervention:To relieve iron load of the body, the patient underwent regular phlebotomy therapy and deferoxamine (DFO) therapy. During the therapy, serum ferritin and hepatitis B virus (HBV) were monitored and the iron concentration of the liver and heart were followed by T2 of magnetic resonance imaging (MRI) scan.Outcomes:Serum ferritin gradually decreased. Approximately 1 year after the therapy, HBsAg turned persistently negative.Lessons:Iron chelation therapy may attenuate HBV infection.

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出版当年[2016]版：

大类 | 2 区医学

小类 | 2 区医学：内科

最新[2025]版：

大类 | 4 区医学

小类 | 4 区医学：内科

JCR分区：

出版当年[2015]版：

Q2 MEDICINE, GENERAL & INTERNAL

最新[2023]版：

Q2 MEDICINE, GENERAL & INTERNAL

影响因子： 1.4 最新[2023版] 1.6 最新五年平均 2.133 出版当年[2015版] 3.195 出版当年五年平均 5.723 出版前一年[2014版] 1.804 出版后一年[2016版]

第一作者：

第一作者机构： [a]Department of Hematology, Xuanwu Hospital, Capital Medical University, Beijing, P. R. China.

通讯作者：

通讯机构： [*1]Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing 100053, China

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