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Compression-distraction reduction surgical verification and optimization to treat the basilar invagination and atlantoaxial dislocation: a finite element analysis

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机构: [1]School of Biomedical Engineering, Capital Medical University, Beijing 100069, China. [2]Beijing Key Laboratory of Fundamental Research on Biomechanics in Clinical Application, Capital Medical University, Beijing 100069, China. [3]Pera Corporation Ltd. Beijing Branch, Beijing 100025, China. [4]Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
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关键词: Basilar invagination Atlantoaxial dislocation Compression-distraction reduction technique Surgical optimization

摘要:
Background: Basilar invagination (BI) combined with atlantoaxial dislocation (AAD) leads to foramen magnum stenosis and medullary spinal cord compression, causing nerve dysfunction. The purpose of the surgery is to remove the bony compression at brainstem ventral side and fix the unstable spinal segment and make it fused stably. Occipital cervical internal fixation system that simultaneously reduces atlantoaxial horizontal and vertical dislocation are established. We propose here a new compression-distraction reduction (CDR) technique. We aimed to construct a congenital BI-AAD preoperative finite element model (FEM) to simulate the CDR technique for AAD reduction surgery. Methods: Based on computed tomographic scans of patients' cervical vertebrae, a three-dimensional (3D) geometric model of the cervical spine (C0-C4) of congenital BIAAD patients was established using Mimics13.1, Geomagic2012, and Space Claim14.0 softwares. The mechanical parameters of the tissues were assigned according to their material characteristics using ANSYS Workbench 14.0 software. A 3D FEM was established using the tetrahedral mesh method. The bending moment was loaded on C0. Physiological conditions-anteflexion, retroflexion, left and right flexion, left and right rotation-were simulated for preoperative verification. The occipital cervical fixation system FEM was established. The CDR technique was simulated to perform AAD reduction surgery. Data were obtained when the atlantoaxial horizontal and vertical dislocation reductions were verified postoperatively. Stress data for the two surgical schemes were analyzed, as was the reduction surgery optimization scheme for congenital BI-AAD patients with abnormal lateral atlantoaxial articulation ossification. Results: Cervical spine (C0-C4) FEM of congenital BI-AAD patients was established. The CDR technique was simulated for AAD reduction. We obtained the mechanical data when the atlantoaxial horizontal and vertical dislocation reductions were satisfied for the two surgical schemes. Conclusions: The CDR technique for AAD reduction was feasible and effective. We propose this reduction optimization scheme for patients with lateral atlantoaxial articulation due to abnormal ossification of congenital BI-AAD. We also provide a biomechanically theoretical basis for improving the reliability of pure posterior reduction surgery and simplifying surgery for complicated BI-AAD disease.

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出版当年[2015]版:
大类 | 3 区 工程技术
小类 | 4 区 工程:生物医学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 工程:生物医学
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出版当年[2014]版:
Q3 ENGINEERING, BIOMEDICAL
最新[2023]版:
Q3 ENGINEERING, BIOMEDICAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2014版] 出版当年五年平均 出版前一年[2013版] 出版后一年[2015版]

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第一作者机构: [1]School of Biomedical Engineering, Capital Medical University, Beijing 100069, China. [2]Beijing Key Laboratory of Fundamental Research on Biomechanics in Clinical Application, Capital Medical University, Beijing 100069, China.
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通讯机构: [1]School of Biomedical Engineering, Capital Medical University, Beijing 100069, China. [2]Beijing Key Laboratory of Fundamental Research on Biomechanics in Clinical Application, Capital Medical University, Beijing 100069, China. [4]Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
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