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High antibiotic resistance rate: A difficult issue for Helicobacter pylori eradication treatment

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收录情况： ◇ SCIE

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机构： [1]Department of Gastroenterology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China

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关键词： Helicobacter pylori Resistance Eradication treatment Triple antibiotic therapy Gastrointestinal disease

摘要：

Helicobacter pylori (H. pylori) infection is associated with a variety of upper gastrointestinal diseases, including gastric cancer. With the wide application of antibiotics in H. pylori eradication treatment, drug-resistant strains of H. pylori are increasing. H. pylori eradication treatment failure affects the outcome of a variety of diseases of the upper gastrointestinal tract. Therefore, antibiotic resistance that affects H. pylori eradication treatment is a challenging situation for clinicians. The ideal H. pylori eradication therapy should be safe, effective, simple, and economical. The eradication rate of triple antibiotic therapy is currently less than 80% in most parts of the world. Antibiotic resistance is the main reason for treatment failure, therefore the standard triple regimen is no longer suitable as a first-line treatment in most regions. H. pylori eradication treatment may fail for a number of reasons, including H. pylori strain factors, host factors, environmental factors, and inappropriate treatment.

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出版当年[2014]版：

大类 | 3 区医学

小类 | 3 区胃肠肝病学

最新[2023]版：

大类 | 3 区医学

小类 | 3 区胃肠肝病学

JCR分区：

出版当年[2013]版：

Q2 GASTROENTEROLOGY & HEPATOLOGY

最新[2023]版：

Q1 GASTROENTEROLOGY & HEPATOLOGY

影响因子： 4.3 最新[2023版] 5.1 最新五年平均 2.433 出版当年[2013版] 2.633 出版当年五年平均 2.547 出版前一年[2012版] 2.369 出版后一年[2014版]

第一作者：

第一作者机构： [1]Department of Gastroenterology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China [*1]Department of Gastroenterology, Xuanwu Hospital, Capital Medical University, No.45 Changchun Street, Xuanwu District, Beijing 100053, China.

通讯作者：

通讯机构： [*1]Department of Gastroenterology, Xuanwu Hospital, Capital Medical University, No.45 Changchun Street, Xuanwu District, Beijing 100053, China.

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